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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The controlled drug delivery technology has progressed over the last six decades. It began in 1952 with the introduction of the first sustained release formulation. The 1st generation (1950-1980) of drug delivery was focused on developing oral and transdermal sustained release systems and establishing the controlled drug release mechanisms.Author: Kinam Park
https://pdfs.semanticscholar.org/03c7/c46ced4ec29135f4fb05562fe0795870dff9.pdf
Controlled release drug delivery systems provide uniform concentration of drug to the absorption site and thus allows the maintainance of plasma concentration within the therapeutic range which minimizes not only the side effects but also the frequency of administration. Classification of rate controlled drug delivery systems:
https://www.pharmatutor.org/articles/oral-controlled-release-drug-delivery-system-review
There are different mechanistic aspects for design of oral controlled release drug delivery systems such as matrix, reservoir, osmotic pressure, ion exchange resins, altered density etc. This article contains brief review on currently existing oral controlled system and various formulation approaches for the controlled release system.Author: M Gahlyan, S Jain
https://ijpras.com/storage/models/article/TeYOGN6dBciE6RSaYCvW8hR2FcFAQVag5S1dwxVGo5yZrYaTt4UG4Qf5nKWQ/gastroretentive-drug-delivery-system-a-review.pdf
The purpose of writing this review on gastroretentive drug delivery systems was to compile the recent literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery.
https://www.academia.edu/3339429/A_REVIEW_ON_ORAL_CONTROLLED_DRUG_DELIVERY
Recently, a new Controlled drug delivery occurs when a polymer generation of pharmaceutical products, called controlled is combined with a drug or active agent such that the release drug delivery systems, such as those developed release from the bulk material is pre-designed.
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
INTRODUCTION: Controlled drug delivery systems can include the maintenance of drug levels within a desired range, the need for fewer administrations, optimal use of the drug in question, and increased patient compliance. higher cost of controlled-release systems compared with …
https://pharmacophorejournal.com/storage/models/article/cG1bD2zldr2XKpMeNXltjKsDy3MIomlPHtTuUKuJssCcBoa5MTA0yalzq12Z/floating-drug-delivery-system-a-review.pdf
The osmotic pressure controlled drug delivery device consists of two components: drug reservoir compartment and an osmotically active compartment. The drug reservoir compartment is enclosed by a pressure responsive collapsible bag, which is impermeable to vapour and liquid and has a drug delivery orifice.File Size: 1MB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Takaya et al. developed pressure controlled colon-delivery capsules prepared using ethylcellulose, which is insoluble in water.62 In such systems, drug release occurs following the disintegration of a water-insoluble polymer capsule because of pressure in the lumen of the colon.Author: Anil K. Philip, Betty Philip
https://www.researchgate.net/publication/260273163_Microparticulate_drug_delivery_system_a_review
Microspheres are a drug delivery system in which the drug is diluted or dispersed homogeneously in the polymer matrix (Kumar et al., 2011). The advantage of a microsphere delivery system is that ...
https://www.researchgate.net/publication/232257568_Drug_delivery_systems_An_updated_review
The main advantage of controlled drug delivery systems is their ability to maintain the required level of a preparation in tissues and biological fluids for a long timelong enough to complete the ...
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