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https://onlinelibrary.wiley.com/doi/10.1002/1521-4095%28200106%2913%3A11%3C837%3A%3AAID-ADMA837%3E3.0.CO%3B2-D
Using mechanical signals to control the release of drugs from polymers is an attractive option for drug administration. Two types of model systems (see Figure), one where the drug molecules do not interact with the polymer matrix and the other where both free and bound drug molecules are present, are considered in this work and the results with three different model drugs incorporated into …Author: K. Y. Lee, M. C. Peters, D. J. Mooney
https://www.researchgate.net/publication/230248691_Controlled_Drug_Delivery_from_Polymers_by_Mechanical_Signals
Mechanical signals are ubiquitous in the body (e.g., compression in cartilage and bone, tension in muscles and tendons and shear stress in blood vessels) and could be harnessed to control ...
https://www.deepdyve.com/lp/wiley/controlled-drug-delivery-from-polymers-by-mechanical-signals-ZzUmTT8DJI
Jan 01, 2001 · Controlled Drug Delivery from Polymers by Mechanical Signals Two types of model systems (see Figure), one where the drug molecules do not interact with the polymer matrix and the other where both free and bound drug molecules are present, are considered in this work and the results with three different model drugs incorporated into hydrogels are reported.
https://www.sciencedirect.com/science/article/pii/S2211383514000252
Smart polymers are becoming increasingly important in the fields of controlled drug delivery, biomedical applications, and tissue engineering, and it is often beneficial to employ polymers that can respond to stimuli which are inherently present in natural systems.Author: Honey Priya James, Rijo John, Anju Alex, K.R. Anoop
https://www.mddionline.com/polymers-controlled-drug-delivery
New materials are enhancing innovative systems currently under development. Controlled drug delivery occurs when a polymer, whether natural or synthetic, is judiciously combined with a drug or other active agent in such a way that the active agent is released from the material in a predesigned manner.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794279/
Advancement in polymer science and engineering has developed new polymers for well-controlled delivery of therapeutic drugs. One of them will be the smart polymer (stimuli-sensitive polymer), which possesses active responsiveness to environmental signals and changes the physicochemical property as designed.Author: Sungwon Kim, Jong-Ho Kim, Oju Jeon, Ick Chan Kwon, Kinam Park
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