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https://www.sciencedirect.com/science/article/pii/S0169409X01001144
The development of control-relevant models for a variety of biomedical engineering drug delivery problems is reviewed in this paper. A summary of each control problem is followed by a review of relevant patient models from literature, an examination of the control approaches taken to solve the problem, and a discussion of the control-relevance of the models used in each case.Author: Robert S. Parker, Francis J. Doyle
https://www.ncbi.nlm.nih.gov/pubmed/11369083
Jun 11, 2001 · The development of control-relevant models for a variety of biomedical engineering drug delivery problems is reviewed in this paper. A summary of each control problem is followed by a review of relevant patient models from literature, an examination of the control approaches taken to solve the problem, and a discussion of the control-relevance of the models used in each case.Author: Robert S. Parker, Francis J. Doyle
https://www.researchgate.net/publication/11969272_Control-relevant_modeling_in_drug_delivery
Request PDF Control-relevant modeling in drug delivery The development of control-relevant models for a variety of biomedical engineering drug delivery problems is reviewed in this paper. A ...
https://www.deepdyve.com/lp/elsevier/control-relevant-modeling-in-drug-delivery-LoKq0J5xJP
Jun 11, 2001 · Control-relevant modeling in drug delivery A summary of each control problem is followed by a review of relevant patient models from literature, an examination of the control approaches taken to solve the problem, and a discussion of the control-relevance of the models …
https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/48/issue/2
Read the latest articles of Advanced Drug Delivery Reviews at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
https://www.researchgate.net/publication/242784947_Role_of_Mathematical_Modeling_in_Controlled_Drug_Delivery
Mathematical modeling of controlled drug delivery can help to provide a scientific knowledge base concerning the mass transport mechanisms that are involved in the control of drug release.
https://link.springer.com/article/10.1007/s10928-005-2103-y
Feb 01, 2005 · Pharmacodynamics were modeled by characterizing tumor growth in both the untreated and drug-treated animals. The resulting PK/PD model related drug administration to effect, and this model has a structure that facilitates future control algorithm synthesis. Control algorithms in this context would directly utilize PK/PD model predictions.Author: John M. Harrold, Julie L. Eiseman, Erin Joseph, Sandra Strychor, William C. Zamboni, Robert S. Parke...
https://link.springer.com/article/10.1007%2Fs10910-019-01050-z
Jul 05, 2019 · This approach connects two aspects of drug delivery, mechanical pumps and prodrugs. Drug delivery monitoring is performed by adjusting the prodrug inflow pressure. We model several dynamic treatment regimes. A combined algorithm of treatment regimes can be used for personalized treatment. A control-aided system allows us to reduce the impact of pumping fluctuations, diffusion slowdown, and drug production …Author: Valdas Laurinavičius, Feliksas Ivanauskas, Anatolij Nečiporenko
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
https://www.aiche.org/conferences/aiche-annual-meeting/2008/proceeding/paper/487g-human-friendly-and-control-relevant-modeling-closed-loop-artificial-pancreas
The main goal of this paper is to present how to design human-friendly and control-relevant modeling experiments, leading to suitable models for a closed-loop artificial pancreas. A series of single-input single-output experiments are designed to reduce the correlation by …
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