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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Targeted drug delivery into the colon is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, Crohn’s disease, amebiosis, colonic cancer, local treatment of colonic pathologies, and systemic delivery of protein and peptide drugs.1, 2 The colon specific drug delivery system (CDDS) should be capable of protecting the drug en route to the colon i.e. drug release …Author: Anil K. Philip, Betty Philip
https://ijpsr.com/bft-article/colon-targeted-drug-delivery-system-a-review/?view=fulltext
Diet, diseased state and food intake influence the pH of the gastrointestinal fluid. The change in pH along the gastrointestinal tract has been used as a means for targeted colon drug delivery 9. There is a pH gradient in the gastrointestinal tract with value ranging from 1.2 in the stomach through 6.6 in the proximal small intestine to a peak of about 7.5 in the distal small intestine (Table 1).
https://www.jgtps.com/admin/uploads/2OLVjN.pdf
colon targeted drug delivery system the drug is targeted to the colon.The colon targeted drug delivery system is used for the treatment of various diseases related to colon like inflammatory bowel disease, crohn’s disease,File Size: 961KB
http://www.pharmatutorjournal.com/index.php/pt/article/view/a-review-on-novel-approaches-for-colon-targeted-drug-delivery-systems
This review mainly focus on targeted drug delivery to the colon is extremely desirable for local treatment of inflammatory bowel disease such as ulcerative colitis, crohn's disease, amoebiasis, colonic cancer as well as for systemic delivery of protein and peptide drugs.Author: Chandan Kumar Singh, Sumedha Saxena, Mukesh Yadav, Alex Laurel Samson
https://www.researchgate.net/publication/244994822_Colon_targeted_drug_delivery_systems-A_review
Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn's disease, ulcerative colitis, etc. but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs,...
https://pdfs.semanticscholar.org/9865/fd2b8d70d640789707547442d58862ad72bb.pdf
The purpose of writing this review on pulsatile drug delivery systems ... Diseases targeted for pulsatile technology . ... activities in the colon. A colon-specific drug delivery system should prevent drug release in the stomach and small intestine, and affect an abrupt onset of drug ...
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