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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800424/
Mar 28, 2011 · Drug delivery by collagen shields depends on loading and a subsequent release of medication by the shield. The collagen matrix acts as a reservoir and the drugs are entrapped in the interstices of the collagen matrix.
https://www.sciencedirect.com/science/article/pii/S0939641198000174
The most successful uses of collagen for controlled drug release are shields in ophthalmology, injectable dispersions for cancer treatment, sponges carrying antibiotics, and implantable minipellets loaded with protein drugs. With the exception of the last mentioned, these functions target local drug delivery.Author: Wolfgang Friess
https://www.sciencedirect.com/science/article/pii/S0169409X1500277X
Collagen is a major component in a wide range of drug delivery systems and biomaterial applications. Its basic physical and structural properties, together with its low immunogenicity and natural turnover, are keys to its biocompatibility and effectiveness.Author: Bo An, Yu-Shan Lin, Barbara Brodsky
https://journals.sagepub.com/doi/pdf/10.7785/tcrt.2012.500331
of the bone drug delivery from different systems still need to be optimized. Collagen and hydroxyapatite (Coll/HA) composites have the potential in mimicking and replacing skeletal bones and might prove to be ideal materials for the design of DDS for bone tissue engineering applications. It has been previ-
https://patents.google.com/patent/US4164559A/en
Solubilized collagen is telopeptides-poor, relatively inexpensive, not antigenic and useful as a biomedical material. Enzyme solubilized native collagen is soluble in acidic pH, insoluble at a physiologic pH and at body temperature. In our previous studies, (Collagen as a Vehicle for Drug Delivery, J. Clin.Author: Teruo Miyata, Albert L. Rubin, Kurt H. Stenzel, Michael W. Dunn
https://www.researchgate.net/publication/320686308_A_review_on_collagen_based_drug_delivery_systems
The main application of collagen is collagen shields which are used in opthalmology. However, fundamental awareness regarding collagen biochemistry and the manufacturing knowledge in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574887/
In the drug delivery process, a drug molecule has to pass through biological barriers on the way from systemic circulation down to tumor cells in tumor microenvironment. If systemic circulation relies on convective (flow) transport, diffusion becomes fundamental transport mode for payload extravasation into tumor microenvironment.
https://www.collagensolutions.com/collagen/applications
Collagen scaffolds can also be used with cells in tissue engineered grafts. In this case, the collagen acts as a substrate for the delivery of cells such as keratinocytes and fibroblasts. Dermal Fillers Soft tissue fillers are injected directly into the skin to minimize the appearance of wrinkles by physically plumping the skin.
https://www.healthline.com/health/food-nutrition/is-hydrolyzed-collagen-a-miracle-cure
Collagen is a protein found in the body of all animals, including humans. It makes up connective tissue like skin, tendons, cartilage, organs, and bones. When collagen is hydrolyzed, it’s broken down into smaller, easy-to-process particles. Those particles are used in products designed to heal everything...Author: The Healthline Editorial Team
https://healthfully.com/what-is-hydrolyzed-collagen-4160023.html
What is Hydrolyzed Collagen. Hydrolyzed collagen is collagen that is derived from bovine bone and cartilage 1. This process results in small, intact amino acids which have not been damaged. These amino acids are quickly absorbed into the bloodstream, and are used as the building blocks of new collagen. History of Hydrolyzed Collagen
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