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https://www.nature.com/articles/nmat1737
Sep 24, 2006 · Co-delivery of drugs and DNA from cationic core–shell nanoparticles self-assembled from a biodegradable copolymer Abstract. Non-viral gene-delivery systems are safer to use and easier to produce than viral vectors,... Main. In this study, we have designed a biodegradable cationic amphiphilic ...Author: Yong Wang, Shujun Gao, Wen-Hui Ye, Ho Sup Yoon, Yi-Yan Yang
http://www.nature.com/articles/doi:10.1038/nmat1737
Sep 24, 2006 · Co-delivery of drugs and DNA has been proposed to enhance gene expression or to achieve the synergistic/combined effect of drug and gene therapies2,3,4,5,6. Attempts have been made to …Author: Yong Wang, Shujun Gao, Wen-Hui Ye, Ho Sup Yoon, Yi-Yan Yang
https://www.ncbi.nlm.nih.gov/pubmed/24094158
Dec 01, 2013 · The hydrophobic PPGMA interior allows a cell-sensitizing drug such as paclitaxel to be incorporated while the cationic and hydrophilic PDMAEMA corona allows the complexation of anionic DNA to form a nano-sized polyplex. These drug-encapsulated copolymers display excellent gene transfection efficiency as compared to PEI or PDMAEMA homopolymers.Author: Xian Jun Loh, Shi Jie Ong, Yin Ting Tung, Hoi Teng Choo
https://ui.adsabs.harvard.edu/abs/2006NatMa...5..791W/abstract
Oct 01, 2006 · Co-delivery of drugs and DNA has been proposed to enhance gene expression or to achieve the synergistic/combined effect of drug and gene therapies. Attempts have been made to deliver drugs and DNA simultaneously using liposomes. Here we report cationic core-shell nanoparticles that were self-assembled from a biodegradable amphiphilic copolymer.Author: Yong Wang, Shujun Gao, Wen-Hui Ye, Ho Sup Yoon, Yi-Yan Yang
https://dr.ntu.edu.sg/handle/10220/8737
Co-delivery of drugs and DNA has been proposed to enhance gene expression or to achieve the synergistic/combined effect of drug and gene therapies. Attempts have been made to deliver drugs and DNA simultaneously using liposomes. Here we report cationic core–shell nanoparticles that were self-assembled from a biodegradable amphiphilic copolymer.
https://www.researchgate.net/publication/6797035_Co-delivery_of_drugs_and_DNA_from_cationic_core-shell_nanoparticles_self-assembled_from_a_biodegradable_copolymer
Co-delivery of drugs and DNA has been proposed to enhance gene expression or to achieve the synergistic/combined effect of drug and gene therapies.
https://www.researchgate.net/publication/257461004_Co-delivery_of_drug_and_DNA_from_cationic_dual-responsive_micelles_derived_from_polyDMAEMA-co-PPGMA
Co-delivery of drug and DNA from cationic dual-responsive micelles derived from poly(DMAEMA-co-PPGMA)
https://www.sciencedirect.com/science/article/pii/S0169409X15002392
Co-delivery of plasmid DNA and anti-cancer drugs using a single carrier The use of a single carrier offers several advantages over separate carriers for co-delivery of multiple therapeutic agents. The consolidation of two therapeutic agents into a single carrier ensures synchronized pharmacokinetics and allows for targeted cells to receive both agents at a ratiometric dose [187] .Author: Pei Yun Teo, Wei Cheng, James L. Hedrick, Yi Yan Yang
https://www.sciencedirect.com/science/article/pii/S2211383515000301
The co-delivery of chemotherapeutic drugs and gene agents provides a promising strategy to overcome drug resistance in cancer therapy. According to recent research, it is clear that combination delivery of gene and drug using nanocarriers is indeed helpful in inhibiting tumor growth compared to gene or drug alone.Author: Lin Kang, Zhonggao Gao, Wei Huang, Mingji Jin, Qiming Wang
https://www.sciencedirect.com/science/article/pii/S0927776513004803
It is also found that the co-delivery of doxorubicin (DOX) and p53-encoding plasmid DNA by the micelles achieved a synergistic effect in suppressing proliferation of HepG2 cells . In addition, such co-delivery system can achieve anticancer effect at lower drug concentration, resulting in …Author: Jie-kan Sun, Ke-feng Ren, Lei-ze Zhu, Jian Ji
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