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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833276/
Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug Resistant Cancer Cells ** Dr. Alex M. Chen , Min Zhang , Dr. Dongguang Wei , Dr. Dirk Stueber , Dr. Oleh Taratula , Dr. Tamara Minko , Prof. , and Dr. Huixin He , Prof.Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
https://www.onlinelibrary.wiley.com/doi/10.1002/smll.200900621
Co‐delivery of Doxorubicin and siRNAs by mesoporous silica nanoparticles into multidrug‐resistance cancer cells with minimal premature release significantly enhances the efficacy of chemotherapy by conquering the nonpump resistance and possibly bypassing the efflux pump resistance (see image).Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
https://www.academia.edu/11966316/Co_delivery_of_Doxorubicin_and_Bcl_2_siRNA_by_Mesoporous_Silica_Nanoparticles_Enhances_the_Efficacy_of_Chemotherapy_in_Multidrug_Resistant_Cancer_Cells
Co‐delivery of Doxorubicin and Bcl‐2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug‐Resistant Cancer Cells
https://www.researchgate.net/publication/26836952_Co-delivery_of_Doxorubicin_and_Bcl-2_siRNA_by_Mesoporous_Silica_Nanoparticles_Enhances_the_Efficacy_of_Chemotherapy_in_Multidrug-Resistant_Cancer_Cells
Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug-Resistant Cancer Cells Article in Small 5(23):2673-7 · December ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620006/
Feb 26, 2013 · Alex MC, Min Z, Dongguang W, Dirk S, Oleh T, Tamara M, Huixin H. Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug-Resistant Cancer Cells. Small. 2009; 5:2673–2677. [PMC free article]Author: Huan Meng, Wilson X. Mai, Haiyuan Zhang, Min Xue, Tian Xia, Sijie Lin, Xiang Wang, Yang Zhao, Zhaoxi...
https://www.researchgate.net/publication/308179484_Dual-Responsive_Mesoporous_Silica_Nanoparticles_Mediated_Co-Delivery_of_Doxorubicin_and_Bcl-2_siRNA_for_Targeted_Treatment_of_Breast_Cancer
Dual-Responsive Mesoporous Silica Nanoparticles Mediated Co-Delivery of Doxorubicin and Bcl-2 siRNA for Targeted Treatment of Breast Cancer September 2016 …
https://europepmc.org/articles/PMC2833276
Dec 01, 2009 · Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells. Alex M Chen Department of Chemistry Rutgers, The State of New Jersey, Newark, NJ 07102, USA.Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
https://pubs.acs.org/doi/abs/10.1021/nn100690m
Dual-Responsive Mesoporous Silica Nanoparticles Mediated Codelivery of Doxorubicin and Bcl-2 SiRNA for Targeted Treatment of Breast Cancer. The Journal of Physical Chemistry C 2016, 120 (39) , 22375-22387. DOI: 10.1021/acs.jpcc.6b06759.Author: Huan Meng, Monty Liong, Tian Xia, Zongxi Li, Zhaoxia Ji, Jeffrey I. Zink, Andre E. Nel
https://pubs.acs.org/doi/10.1021/acs.jpcc.6b06759
The combination of chemotherapy and gene therapy could induce the enhanced therapeutic efficacy in the cancer therapy. To achieve this goal, a new mesoporous silica nanoparticles (MSNs)-based codelivery system was developed for targeted simultaneous delivery of doxorubicin (DOX) and Bcl-2 small interfering RNA (siRNA) into breast cancer cells.Author: Xiaojun Zhou, Liang Chen, Wei Nie, Weizhong Wang, Ming Qin, Xiumei Mo, Hongsheng Wang, Chuanglong He
https://pubs.acs.org/doi/suppl/10.1021/acs.jpcc.6b06759/suppl_file/jp6b06759_si_001.pdf
Dual-Responsive Mesoporous Silica Nanoparticles Mediated Co-Delivery of Doxorubicin and Bcl-2 siRNA for Targeted Treatment of Breast Cancer ... siRNA, and lane 3-5: the cells were treated with MSNs-PPPFA/Bcl-2 siRNA complexes at weight ratio of nanoparticles to siRNA of 5:1, 10:1 and 20:1.
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