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https://www.sciencedirect.com/science/article/pii/S0168365911010820
Serum proteins, especially transferrin and primarily albumin, are playing an increasing role in the design of new pharmaceuticals and two albumin-based drug delivery systems, the albumin-paclitaxel nanoparticle Abraxane® in oncology and Levemir®, an albumin-binding human insulin for treating diabetes, have established themselves as blockbusters.Author: Felix Kratz, Bakheet Elsadek
https://www.ncbi.nlm.nih.gov/pubmed/22155554
Jul 20, 2012 · Clinical impact of serum proteins on drug delivery. Kratz F(1), Elsadek B. Author information: (1)Tumor Biology Center, Division of Macromolecular Prodrugs, Breisacher Strasse 117, 79106 Freiburg, Germany. [email protected]: Felix Kratz, Bakheet Elsadek
https://www.sciencedirect.com/science/article/abs/pii/S0168365911010820
Among serum proteins albumin and transferrin have attracted the most interest as drug carriers in the past two decades. Prior to that, their potential use was overshadowed by the advent of monoclonal antibodies that was initiated by Milstein and Koehler in 1975.Author: Felix Kratz, Bakheet Elsadek
https://www.researchgate.net/publication/51865755_Clinical_impact_of_serum_proteins_on_drug_delivery
Clinical impact of serum proteins on drug delivery Article · Literature Review in Journal of Controlled Release 161(2):429-45 · December 2011 with 81 Reads How we measure 'reads'
https://courses.helsinki.fi/sites/default/files/course-material/4512165/4%20Clinical%20impact%20of%20serum%20proteins%20on%20drug%20delivery.pdf
Review Clinical impact of serum proteins on drug delivery Felix Kratz a,⁎, Bakheet Elsadek b a Tumor Biology Center, Division of Macromolecular Prodrugs, Breisacher Strasse 117, 79106 Freiburg, Germany b Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, 71524 Assiut, Egypt article info abstract Article history: Received 17 August 2011
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975355/
Feb 27, 2014 · Human serum albumin (HSA) is an abundant plasma protein, which attracts great interest in the pharmaceutical industry since it can bind a remarkable variety of drugs impacting their delivery and efficacy and ultimately altering the drug’s pharmacokinetic and pharmacodynamic properties.Author: Feng Yang, Yao Zhang, Hong Liang
http://www.eurekaselect.com/155760/article
Title:Cysteine-rich Proteins for Drug Delivery and Diagnosis VOLUME: 26 ISSUE: 8 Author(s):Guang Yang*, Yue Lu, Hunter N. Bomba and Zhen Gu* Affiliation:Key Laboratory of Science & Technology of Eco-Textile, Donghua University, Ministry of Education, Shanghai 201620, Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill, and North Carolina State …Author: Guang Yang, Yue Lu, Hunter N. Bomba, Zhen Gu
https://www.researchgate.net/publication/335117559_Complexation_of_cis-Pt_and_trans-PtNH32Cl2_with_serum_proteins_A_potential_application_for_drug_delivery
Serum proteins are known to play an important role as drug delivery systems with important clinical applications. The loading efficacy of cis-Pt(NH3)2Cl2 and trans-Pt(NH3)2Cl2 with human serum ...
https://en.wikipedia.org/wiki/Ozoralizumab
Ozoralizumab is a humanized monoclonal antibody designed for the treatment of inflammatory diseases.. Ozoralizumab was developed by Pfizer Inc, and now belongs to Ablynx NV. Ablynx has licensed the rights to the antibody in China to Eddingpharm.. ReferencesATC code: none
http://www.snec.com.sg/research-innovation/research-impact/clinical-impact
With the emergence of sustained-release drug delivery systems for common glaucoma drugs, issues arising from missed applications can be addressed and significantly reduced. SERI has completed a pilot clinical trial on a sustained-release drug delivery system, developed in collaboration with NTU.
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