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https://www.ncbi.nlm.nih.gov/pubmed/26536406
Chronotherapy coordinates drug delivery with the circadian rhythm to enhance effectiveness and mitigate adverse effects and is achieved by delivering a drug when the system is most susceptible. Cancer is a chronotherapeutic disorder.Author: Paul Librodo, Mitchell Buckley, Marilyn Luk, Andrea Bisso
http://www.bioline.org.br/pdf?pr09060
Trop J Pharm Res, October 2009; 8 (5): 469 throughout a 24-hour period, may be changing as researchers' report that some medications may work better if their administration is coordinated with day-night patterns and biological rhythms [1]. Diseases and chronotherapeutics Up to now, design of drug delivery systems
https://www.researchgate.net/publication/51561273_Chronotherapeutic_Drug_Delivery_Systems_-_An_Approach_to_Circadian_Rhythms_Diseases
The purpose of writing this review on chronotherapeutic drug delivery systems (ChrDDs) is to review the literatures with special focus on ChrDDs and the various dosage forms, techniques that are ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762207/
A Multilayered Multidisk Tablet (MLMDT) comprising two drug-loaded disks enveloped by three drug-free barrier layers was developed for use in chronotherapeutic disorders, employing two model drugs, theophylline and diltiazem HCl. The MLMDT was designed ...Author: Zaheeda Khan, Yahya E. Choonara, Pradeep Kumar, Lisa C. du Toit, Valence M. K. Ndesendo, Viness Pill...
https://journals.lww.com/journalofinfusionnursing/Abstract/2012/09000/Chronotherapeutic_Drug_Delivery.8.aspx
and is achieved by delivering a drug when the system is most susceptible. Cancer is a chronotherapeutic disorder. Cancer treatment requires high doses of intravenous medication to kill cancerous cells; however, normal cells are also killed, creating intolerable side effects. This review shows that chronotherapy can play a vital role in the quality of life and survival rate for oncology ...
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