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https://www.researchgate.net/publication/51561273_Chronotherapeutic_Drug_Delivery_Systems_-_An_Approach_to_Circadian_Rhythms_Diseases
The purpose of writing this review on chronotherapeutic drug delivery systems (ChrDDs) is to review the literatures with special focus on ChrDDs and the various dosage forms, techniques that are ...
http://www.bioline.org.br/pdf?pr09060
Trop J Pharm Res, October 2009; 8 (5): 469 throughout a 24-hour period, may be changing as researchers' report that some medications may work better if their administration is coordinated with day-night patterns and biological rhythms [1]. Diseases and chronotherapeutics Up to now, design of drug delivery systems
https://www.ncbi.nlm.nih.gov/pubmed/26536406
Chronotherapy coordinates drug delivery with the circadian rhythm to enhance effectiveness and mitigate adverse effects and is achieved by delivering a drug when the system is most susceptible. Cancer is a chronotherapeutic disorder.Author: Paul Librodo, Mitchell Buckley, Marilyn Luk, Andrea Bisso
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548250/
Jul 01, 2011 · In other words, they require pulsatile drug delivery system (PDDS). The pulsatile system is gaining a lot of interest, as the drug is released completely after defined lag time (Fig. 1). Pulsatile drug delivery is time and site-specific drug delivery, thus providing spatial and temporal delivery and increasing patient compliance.Author: Deepika Jain, Richa Raturi, Vikas Jain, Praveen Bansal, Ranjit Singh
http://www.authorstream.com/Presentation/mammi014-2885978-chronotherapeutic-drug-delivery-system/
Aug 09, 2016 · LIMITATIONS OF PULSATILE DRUG DELIVERY SYSTEM : Pulsatile drug delivery system have certain limitation, so in many cases these drug delivery system is fails, • Multiple manufacturing steps in case of Multi particulate pulsatile drug delivery system. • Low drug load • Incomplete release • In-vivo variability in single unit pulsatile drug ...
http://www.jocpr.com/articles/current-status-of-chronotherapeutic-drug-delivery-system-an-overview.pdf
pulsed, triggered and programmed drug delivery devices have been developed and extensively studied in recent years for chronopharmaceutical drug delivery. These, as well as pertinent issues, are addressed in this review. Key words: Cicardian rhythm, Chronotherapeutics, Chronopharmacology, chronotherapeutic drug delivery system.
https://www.researchgate.net/publication/227943914_Development_and_evaluation_of_a_chronotherapeutic_drug_delivery_system_of_torsemide
Development and evaluation of a chronotherapeutic drug delivery system of torsemide Article (PDF Available) in Brazilian Journal of Pharmaceutical Science 47(3):593-600 · July 2011 with 125 Reads
http://www.authorstream.com/Presentation/swatijaiswalbhu-1165558-chronotherapeutic-drug-delivery/
Aug 28, 2011 · Chronotherapeutic Drug Delivery - authorSTREAM Presentation. introduction: introduction Recent studies have revealed that diseases have a predictable cyclic rhythm and that the timing of medication regimens can improve the outcome of a desired effect.
https://journals.lww.com/journalofinfusionnursing/Abstract/2015/11001/Chronotherapeutic_Drug_Delivery.4.aspx
and is achieved by delivering a drug when the system is most susceptible. Cancer is a chronotherapeutic disorder. Cancer treatment requires high doses of intravenous medication to kill cancerous cells; however, normal cells are also killed, creating intolerable side effects. This review shows that chronotherapy can play a vital role in the quality of life and survival rate for oncology ...
https://www.japsonline.com/admin/php/uploads/2155_pdf.pdf
Pulsatile drug delivery system is defined as the rapid and transient release of certain amount of drug molecules within a short time period immediately after a predetermined off-release period, i.e. lag time. This delivery system aims to release the drug site of action (Singh et al., 2016).
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