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https://www.tandfonline.com/doi/abs/10.1517/17425247.2010.495981
Mar 06, 2015 · Importance of the field: Chitosan represents a multifunctional polymer, featuring both mucoadhesive and permeation-enhancing properties and therefore is a widely studied excipient for mucosal drug delivery. As regards nasal administration, chitosans have been used for the preparation of gels, solid inserts, powders and nanoparticles in which a three-dimensional network can be …Author: Barbara Luppi, Federica Bigucci, Teresa Cerchiara, Vittorio Zecchi
https://www.sciencedirect.com/science/article/pii/S0141813019327217
In this regard, deoxycholate-chitosan-hydroxybutyl nanoparticles with CTZ covalently grafted and free CTZ encapsulated (CTZ:CDHBCs-NPs) were synthesized as nasal adaptive nano-drug delivery …Author: Mengjie Sun, Xiaoping Yu, Ting Wang, Shichao Bi, Ya Liu, Xiguang Chen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245419/
To maximize drug permeation through the nasal mucosa, it is critical for intranasal drug delivery systems to have enhanced nasal absorption . Chitosan has been shown to increase nasal absorption due to its properties of mucoadhesion and ability to increase membrane permeability ( 22 – 25 ).Author: Sarah Baltzley, Atiquzzaman Mohammad, Ahmad H. Malkawi, Abeer M. Al-Ghananeem
https://www.sciencedirect.com/science/article/pii/S0939641112001038
Such mucoadhesive systems can be in the form of powders as well as liquids or liquid in situ gelling systems such as described above. Mainly because of its mucoadhesive and permeation enhancing properties, chitosan has been investigated as auxiliary agent in nasal drug delivery systems [49], [50].Author: Andreas Bernkop-Schnürch, Sarah Dünnhaupt
https://www.tandfonline.com/doi/abs/10.1080/17425247.2019.1597051
Feb 26, 2019 · (2019). Smart thermosensitive chitosan hydrogel for nasal delivery of ibuprofen to treat neurological disorders. Expert Opinion on Drug Delivery: Vol. 16, No. 4, pp. 453-466.Author: Hanieh Gholizadeh, Shaokoon Cheng, Michele Pozzoli, Elisa Messerotti, Daniela Traini, Paul Young, Ag...
https://www.researchgate.net/publication/224914485_Chitosan-based_drug_delivery_systems
Lately, the transmucosal absorption promoting characteristics of chitosan has been exploited especially for nasal and oral delivery of polar drugs to include peptides and proteins and for vaccine ...
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