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https://www.hindawi.com/journals/jnm/2011/952060/
This study examines properties of the PLGA-chitosan nanoparticle/plasmid DNA complex after formation. Specifically, the study aims to determine the optimal ratio of plasmid DNA:nanoparticles for nucleic acid delivery purposes and to elucidate the location of the pDNA within these complexes.Author: Hali Bordelon, Alexandru S. Biris, Cristina M. Sabliov, W. Todd Monroe
https://www.sciencedirect.com/science/article/pii/S0378517309005006
The aim of this study was to adapt the ionic gelation technique for the encapsulation of different nucleic acids (plasmid DNA and short oligonucleotides) into chitosan nanoparticles and to evaluate their potential as gene delivery nanocarriers.Author: Noemi Csaba, Magnus Köping-Höggård, Maria Jose Alonso
https://www.tandfonline.com/doi/pdf/10.1080/10717540490280705
CHITOSAN NANOPARTICLES FOR pDNA DELIVERY 109 FIG. 2. Schematic presentation of the nanoparticle preparation by the solvent evaporation method. solution was mixed with ethanol at 2.5 mg/mL. pDNA was sus-
https://www.ncbi.nlm.nih.gov/pubmed/15200009
Chitosan nanoparticles for plasmid DNA delivery: effect of chitosan molecular structure on formulation and release characteristics. Bozkir A(1), Saka OM. Author information: (1)Department of Pharmaceutical Technology, Faculty of Pharmacy, Ankara University, Ankara, Turkey. [email protected]: Asuman Bozkir, Ongun Mehmet Saka
https://www.researchgate.net/publication/8507662_Chitosan_Nanoparticles_for_Plasmid_DNA_Delivery_Effect_of_Chitosan_Molecular_Structure_on_Formulation_and_Release_Characteristics
The chitosan-plasmid DNA nanoparticles were formulated using complex coacervation and solvent evaporation technique, showing that the release of plasmid …
https://www.ncbi.nlm.nih.gov/pubmed/21226549
Topical application of plasmid DNA represents an attractive route of gene delivery. Although chitosan (CS) has been widely investigated as a gene-carrier, there is very limited information about the skin application of CS-based systems for DNA. This study evaluated pDNA-loaded chitosan nanoparticles (CS-NPs) for skin gene delivery.Author: Suna Özbaş-Turan, Jülide Akbuğa
https://www.tandfonline.com/doi/abs/10.1080/10717540490280705
Oct 07, 2008 · Chitosan can be useful as a nonviral vector for gene delivery. Although there are several reports to form chitosan-pDNA particles, the optimization and effect on transfection remain insufficient. The chitosan-pDNA nanoparticles were formulated using …Author: Asuman Bozkir, Ongun Mehmet Saka
https://www.sciencedirect.com/science/article/pii/S1050464818303255
Feed pellets containing chitosan nanoparticles as plasmid DNA oral delivery system for fish: In vivo assessment in gilthead sea bream (Sparus aurata) ... (Sparus aurata) following oral or intramuscular administration of plasmid DNA in chitosan nanoparticles. Aquaculture, 474 (2017), pp. 1-10, 10.1016/j.aquaculture.2017.03.023.Author: M.I. Sáez, A.J. Vizcaíno, F.J. Alarcón, T.F. Martínez
https://academic.oup.com/abbs/article/41/6/515/797
May 09, 2009 · Chitosan (CS), a biocompatible and biodegradable material, can act as a non-viral delivery vehicle with low toxicity. In this study, plasmid DNA (pDNA) and siRNA were encapsulated in CS nanoparticles (NPs) to prepare CS–DNA and CS–siRNA NPs using a complex coacervation process.Author: Yujing Yuan, Jieyi Tan, Yifei Wang, Chuiwen Qian, Meiying Zhang
https://dl.acm.org/doi/10.1155/2015/371529
Synthesis and characterization of chitosan-saponin nanoparticle for application in plasmid DNA delivery. ... "Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency," Journal of Controlled Release, vol. 70, no. 3, ...Author: BandeFaruku, ArshadSiti Suri, BejoMohd Hair, KambaShafiu Abdullahi, OmarAbdul Rahman
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