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https://www.sciencedirect.com/science/article/pii/S0169409X09002828
In addition, thermosensitive hydrogel variants have been developed to form a chitosan hydrogel in situ, precluding the need for surgical implantation. The development of these intelligent drug delivery devices requires a foundation in the chemical and physical characteristics of chitosan-based hydrogels, as well as the therapeutics to be delivered.Author: Narayan Bhattarai, Jonathan Gunn, Miqin Zhang
https://www.sciencedirect.com/science/article/pii/S0144861718307690
Advanced development of chitosan hydrogels has led to new drug delivery systems that can release their active ingredients in response to environmental stimuli. This review considers more recent investigation of chitosan hydrogel preparations and the application of these preparations for drug delivery in wound dressings.Author: Hamid Hamedi, Sara Moradi, Samuel M. Hudson, Alan E. Tonelli
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578208/
The pH sensitive hydrogels allocate drug delivery to specified sites such as stomach or intestine and increase drug bioavailability. Colon drug delivery systems of chitosan based hydrogels can be designed for relief of diseases such as irritable or inflammatory bowel diseases (116,117).
https://www.hindawi.com/journals/bmri/2017/3564060/
Thermosensitive hydrogels have increasingly received considerable attention for local drug delivery based on many advantages. However, burst release of drugs is becoming a critical challenge when the hydrogels are employed. Microspheres- (MS-) loaded thermosensitive hydrogels were thus fabricated to address this limitation. Employing an orthogonal design, the spray-dried operations of ...Author: Ting-Ting Yang, Yuan-Zheng Cheng, Meng Qin, Yong-Hong Wang, Hong-Li Yu, An-Lin Wang, Wei-Fen Zhang
https://www.ncbi.nlm.nih.gov/pubmed/19799949
Jan 31, 2010 · The advanced development of chitosan hydrogels has led to new drug delivery systems that release their payloads under varying environmental stimuli. In addition, thermosensitive hydrogel variants have been developed to form a chitosan hydrogel in situ, precluding the …Author: Narayan Bhattarai, Jonathan Gunn, Miqin Zhang
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the …Author: Jianyu Li, David J. Mooney
https://pubs.acs.org/doi/10.1021/acsabm.9b00733
Nov 06, 2019 · An injectable hydrogel of chemically modified chitosan has been developed for controlled drug delivery application. Highly hydrophilic chitosan is chemically modified through grafting of ester-diol based polyurethane to transform into hydrogel through hydrophilic–hydrophobic balance. Grafting is confirmed through different spectroscopic techniques such as 13C NMR, UV–visible, and FTIR ...Author: Arun Kumar Mahanta, Pralay Maiti
https://www.researchgate.net/publication/333616179_Chitin_and_Chitosan_in_Drug_Delivery
The present study provided a basis for the future development of the chitosan-based temperature-sensitive hydrogel in ophthalmic drug delivery. ... non-parenteral drug delivery, chitosan ...
https://www.researchgate.net/publication/229895107_Preparation_of_Chitosan-Based_Thermosensitive_Hydrogels_for_Drug_Delivery
In previous study, we had developed chitosan/-glycerophosphate thermosensitive hydrogel as a drug delivery carrier [14, 15]. The results showed that the prepared hydrogel was liquid at room ...
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