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https://www.sciencedirect.com/science/article/pii/S1740674905000132
Recent human and animal studies have indicated that chitosan-based delivery systems are promising alternatives to conventional formulation approaches for the mucosal delivery of biotechnology drugs, such as proteins and genes.Author: Mohamed M. Issa, Magnus Köping-Höggård, Per Artursson
https://www.researchgate.net/publication/240195791_Chitosan_and_the_mucosal_delivery_of_biotechnology_drugs
This review discussed the biological and pharmaceutical considerations for intranasal drug delivery, application of chitosan in the intranasal drug delivery field, dosage forms based on chitosan ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255357/
This update review is on mucoadhesive polymers used in nasal dosage forms. The nasal mucosa provides a potentially good route for systemic drug delivery. One of the most important features of the nasal route is that it avoids first-pass hepatic metabolism, thereby reducing metabolism. The ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414903/
Mar 05, 2018 · Palmitoyl glycol chitosan is a hydrophobically-modified glycol chitosan. Its use in drug delivery started since the 1990s.The presence of both of hydrophilic and hydrophobic groups imparts it an amphiphilic character [125,126]. It has ability to self-assemble into vesicles suitable for delivery of water-soluble drugs such as bleomycin . Its ...Author: Twana Mohammed M. Ways, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://pubs.acs.org/doi/abs/10.1021/bm0496211
Sep 25, 2004 · Chitosan nanoparticles (CS NPs) of a controlled size (below 100 nm) and narrow size distribution were obtained through the process of ionic gelation between CS and sodium tripolyphosphate (TPP). A high degree of CS deacetylation and narrow polymer molecular weight distribution were demonstrated to be critical for the controlling particle size distribution.Author: Hong Zhang, Megan Oh, Christine Allen, Eugenia Kumacheva
https://www.sciencedirect.com/science/article/pii/S0141813017338928
Chitosan the second most abundant next to cellulose, naturally occurring amino polysaccharide, derived as a deacetylated form of chitin. Its nontoxic, biocompatible, antibacterial and biodegradable properties have led to significant research towards biomedical and pharmaceutical applications, such as drug delivery, tissue engineering, wound-healing dressing etc.Author: Akbar Ali, Shakeel Ahmed
https://onlinelibrary.wiley.com/doi/10.1211/0022357022476
This paper presents an overview of the potential of chitosan‐based systems for improving the retention and biodistribution of drugs applied topically onto the eye. Besides its lAuthor: María José Alonso, Alejandro Sánchez
https://www.e-bookdownload.net/search/mucosal-delivery-of-biopharmaceuticals
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https://www.mdpi.com/2079-4983/3/3/615/pdf
improving mucosal and trans-mucosal delivery or drugs, mainly due to their mucoadhesive and absorption enhancing properties, closely related with the cationic character of the polymer [3–5]. Indeed, due to its positive charge, chitosan has the special feature of adhering to mucosal surfaces,Author: Susana Rodrigues, Marita Dionísio, Carmen Remuñán López, Ana Grenha
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