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https://www.ncbi.nlm.nih.gov/pubmed/20939686
Challenges and opportunities in respiratory drug delivery devices. Nikander K. Recent reviews conclude that there is a need to improve the management of respiratory diseases treated with inhaled drugs, mainly asthma and chronic obstructive pulmonary disease (COPD).Author: Kurt Nikander
https://www.tandfonline.com/doi/abs/10.1517/17425247.2010.525231
Jan 09, 2014 · Challenges and opportunities in respiratory drug delivery devices Kurt Nikander Clinical Research and Development, Respiratory Drug Delivery, Philips Home Healthcare Solutions, Parsippany, NJ 07054, USA +1 978 594 0350; [email protected]: Kurt Nikander
https://www.researchgate.net/publication/47403047_Challenges_and_opportunities_in_respiratory_drug_delivery_devices
Challenges and opportunities in respiratory drug delivery devices. Recent reviews conclude that there is a need to improve the management of respiratory diseases treated with inhaled drugs, mainly asthma and chronic obstructive pulmonary disease (COPD).Author: Kurt Nikander
https://www.optinose.com/exhalation-delivery-systems/nasal-delivery-challenges
Effective, targeted drug delivery for many therapeutic applications requires reaching the high and deep part of the nasal passages, which means drug must be delivered beyond the nasal valve and above the inferior turbinate bone to reach the broad surfaces lined by lung-like respiratory epithelium that surround sinus openings and where the nerves from the brain penetrate to carry sense of smell.
https://www.future-science.com/doi/full/10.4155/tde-2017-0037
Jul 21, 2017 · Pulmonary drug delivery is relatively complex because the respiratory tract has evolved defense mechanisms to keep inhaled drug particles out of the lungs and to remove or inactivate them once deposited. In addition to these mechanical, chemical and immunological barriers,...Author: Stephen P Newman
https://www.medicalplasticsnews.com/news/medical-devices/smart-thinking_1/
Jun 20, 2017 · Smart devices and connectivity were addressed in a joint workshop in April 2017 by Welch and his colleague Kevin Deane, executive VP, Front End Innovation at Medicom Innovation Partner at the RDD Europe Respiratory Drug Delivery conference in Antibes, France.
https://biotechpharmasummit.com/wp-content/uploads/2019/05/Inhalation_and_Respiratory_Drug_Delivery_Summit_Official_Program_2019.pdf
Respiratory Drug Delivery 2019 conference. This year’s event is designed for senior indus-try experts that will showcase new trends in aerosol science and the future directions of inhalation drug delivery research. Further discussion focusses on the regulatory pathways for inhaled therapies and challenges of bringing respiratory products to market.
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is becoming increasingly used. When developing pulmonary drugs, pharmaceutical chemists must consider drug absorption, control of particle size, suitable toxicology models, and patient compliance. The author reviews the issues specific to developing drugs designed for pulmonary delivery and considers how—with the right knowledge and expertise—these challenges …
https://www.meddeviceonline.com/doc/what-s-next-in-inhalation-drug-delivery-0001
Jan 10, 2017 · By Scott Danhof and Felicia Hobson, Battelle. Millions of people depend on inhalation drug delivery devices to control chronic conditions such as asthma or COPD, as well as treat acute respiratory attacks and infectious diseases. Many of the devices on the market today have not changed significantly in decades.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · Pulmonary drug delivery is an attractive route of administration for diverse entities including micro and macromolecules such as vaccines, DNA, cytokines, antibodies, and hormones.16 Therefore, it is essential that the hardware technology of inhalers meets the needs of the pulmonary delivery of such diverse molecules. Devices should be manufactured to ensure maximal stability for …Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
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