We have collected information about Challenges And Advances In Nanoparticle-Based Oral Insulin Delivery for you. Follow the links to find out details on Challenges And Advances In Nanoparticle-Based Oral Insulin Delivery.
https://www.researchgate.net/publication/38087947_Challenges_and_advances_in_nanoparticle-based_oral_insulin_delivery
Challenges and advances in nanoparticle-based oral insulin delivery Article · Literature Review in Expert Review of Medical Devices 6(6):665-76 · November 2009 with 104 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pubmed/19911877
Challenges and advances in nanoparticle-based oral insulin delivery. Ramesan RM(1), Sharma CP. Author information: (1)Biosurface Technology Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.Author: Rekha M Ramesan, Chandra P Sharma
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
The oral route of insulin administration may be the most patient-friendly way of taking insulin and it could more closely mimic physiological insulin delivery (more portal insulin concentration than peripheral). However, the challenges in making oral insulin include: Inactivation by proteolytic enzymes in the GI tract and low permeability ...
https://www.sciencedirect.com/science/article/pii/S0168365917308283
In order to alleviate the above adverse effects, a number of nanoparticle-based delivery systems have emerged to elevate oral insulin absorption , , . These nanocarriers aim to overcome the enzymatic degradation in the stomach and improve permeation through the gastrointestinal (GI) tract.Author: Chun Y. Wong, Hani Al-Salami, Crispin R. Dass
https://www.sciencedirect.com/science/article/pii/S1021949815000356
Whether these insulin-loaded nanocarriers can be launched in the market in the future still has many challenges. Therefore, continuous investigation and optimization of nanoparticle-based delivery systems for insulin oral delivery in diabetics are anticipated. Conflicts of interest. The authors have no conflicts of interest to declare.Author: Milind Sadashiv Alai, Wen Jen Lin, Shailaja Suresh Pingale
https://link.springer.com/article/10.1208%2Fs12249-012-9807-2
May 30, 2012 · In the present study, we developed novel insulin-loaded hyaluronic acid (HA) nanoparticles for insulin delivery. The insulin-loaded HA nanoparticles were prepared by reverse-emulsion-freeze-drying method. This method led to a homogenous population of small HA nanoparticles with average size of 182.2 nm and achieved high insulin entrapment efficiencies (approximately 95%).Author: Lina Han, Yuefang Zhao, Lifang Yin, Ruiming Li, Yang Liang, Huan Huang, Shirong Pan, Chuanbin Wu, Mi...
https://www.researchgate.net/publication/294732711_Insulin_delivery_methods_Past_present_and_future
Insulin delivery methods: Past, present and future. ... Challenges and advances in . nanoparticle-based oral insulin delivery. Expert Rev Med .
https://www.pharmaceutical-journal.com/research/review-article/recent-advances-in-the-oral-delivery-of-biologics/20207374.article
Research in the area of oral delivery of biologics has a long and rich history, and the proliferation of biologics in recent decades has further accelerated research activity. This article summarises the main physiological barriers to oral delivery of biologics and discusses different research strategies to enable, or improve, their oral delivery.
https://link.springer.com/chapter/10.1007/978-94-007-6010-3_4
Jan 29, 2013 · Ribeiro A.J., Seiça R., Veiga F. (2013) Nanoparticles for Oral Delivery of Insulin. In: Coelho J. (eds) Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment. Advances in Predictive, Preventive and Personalised Medicine, vol 4. Springer, Dordrecht. First Online 29 January 2013Author: Antonio J. Ribeiro, Raquel Seiça, Francisco Veiga
https://pubs.acs.org/doi/abs/10.1021/bm0703923
The pharmacological activity of insulin-loaded dextran sulfate/chitosan nanoparticles was evaluated following oral dosage in diabetic rats. Nanoparticles were mucoadhesive and negatively charged with a mean size of 500 nm, suitable for uptake within the gastrointestinal tract. Insulin association efficiency was over 70% and was released in a pH-dependent manner under simulated gastrointestinal ...Author: Bruno Sarmento, António Ribeiro, Francisco Veiga, Domingos Ferreira, Ronald Neufeld
Searching for Challenges And Advances In Nanoparticle-Based Oral Insulin Delivery?
You can just click the links above. The data is collected for you.
