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https://www.nature.com/articles/nbt1223
Jun 25, 2006 · Technologies that mediate targeted delivery of small interfering RNAs (siRNAs) are needed to improve their therapeutic efficacy and safety. Therefore, we have developed aptamer-siRNA chimeric RNAs ...Author: James O McNamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A ...
https://www.ncbi.nlm.nih.gov/pubmed/16823371
Technologies that mediate targeted delivery of small interfering RNAs (siRNAs) are needed to improve their therapeutic efficacy and safety. Therefore, we have developed aptamer-siRNA chimeric RNAs capable of cell type-specific binding and delivery of functional siRNAs into cells.Author: James O McNamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A ...
https://www.gene-quantification.de/mcnamara-sirna-2006.pdf
Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras James O McNamara II1,3, Eran R Andrechek2,3, Yong Wang1, Kristi D Viles1, Rachel E Rempel2, Eli Gilboa1, Bruce A Sullenger1 & Paloma H Giangrande1 Technologies that mediate targeted delivery of small interfering RNAs (siRNAs) are needed to improve their therapeutic efficacy
http://ccc.chem.pitt.edu/wipf/Current%20Literature/Julia_2.pdf
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras Julia Vargas November 25th, 2006 Sullenger, B. A. et al Duke Center for Translational Research,
https://www.researchgate.net/publication/6962426_Cell_type-specific_delivery_of_siRNAs_with_aptamer-siRNA_chimeras
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. ... we have developed aptamer-siRNA chimeric RNAs capable of cell type-specific binding and delivery of functional siRNAs into ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(06)00358-3
This Journal Full Site. Advanced Search. Log in; RegisterAuthor: James O McNamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A ...
https://www.researchgate.net/publication/237683162_83_Cell-Type_Specific_Delivery_of_siRNAs_with_Aptamer-siRNA_Chimeras
Cell-Type Specific Delivery of siRNAs with Aptamer-siRNA Chimeras Article (PDF Available) in Molecular Therapy 13 · May 2006 with 107 Reads How we measure 'reads'
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(16)30107-X
Jan 01, 2012 · Oligonucleotide aptamer-mediated in vivo cell targeting of small interfering RNAs (siRNAs) is emerging as a useful approach to enhance the efficacy and reduce the adverse effects resulting from siRNA-mediated genetic interference. A current main impediment in aptamer-mediated siRNA targeting is that the activity of the siRNA is often compromised when conjugated to an aptamer, often requiring ...Author: Alexey Berezhnoy, Randall Brenneman, Marcio Bajgelman, Dawn Seales, Eli Gilboa
https://www.academia.edu/18219877/Cell_type_specific_delivery_of_siRNAs_with_aptamer-siRNA_chimeras
Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791695/
In principle, the aptamer-siRNA chimera approach can be applied to develop reagents targeting many different cell types provided that a cell-type-specific receptor exists and that an aptamer against the receptor can be selected. The development of an aptamer-siRNA chimera that targets HIV-infected cells supports this notion 32.Author: Justin P Dassie, Xiu-ying Liu, Gregory S Thomas, Ryan M Whitaker, Kristina W Thiel, Katie R Stockdal...
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