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https://www.researchgate.net/publication/8108606_Cationic_Vectors_in_Ocular_Drug_Delivery
Cationic Vectors in Ocular Drug Delivery. ... One of the approaches recently developed is the drug incorporation into cationic submicronic vectors which exploit the negative charges present at the ...
https://www.tandfonline.com/doi/abs/10.1080/10611860400015910
Despite extensive research in the field, the major problem in the ocular drug delivery domain still is rapid precorneal drug loss and poor corneal permeability. One of the approaches recently developed is the drug incorporation into cationic submicronic vectors which exploit the negative charges present at the corneal surface for increased residence time and penetration.This review will focus ...Author: Laura Rabinovich-Guilatt, Patrick Couvreur, Gregory Lambert, Catherine Dubernet
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/cationic-surfactants
Cationic Surfactants. ... This is the case for colloidal systems aimed for ocular drug delivery, where positively charged aggregates interact with a negatively charged ocular surface to provide longer contact time. ... Furthermore, inclusion of cationic amphiphiles has an impact on drug release. Smart delivery systems, based on cationic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313063/
Feb 27, 2012 · 2. Cationic Nanoemulsion for Ocular Delivery. As the neuroretina is an extension of the central nervous system, the external eye and its adnexa are designed to protect the internal ocular structures, particularly from harmful chemicals [].The first ocular barrier is the eyelid which acts as a shutter preventing foreign substances from contact with the ocular surface.Author: Frederic Lallemand, Philippe Daull, Simon Benita, Ronald Buggage, Jean-Sebastien Garrigue
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.hindawi.com/journals/jdd/2012/604204/
The potential of cationic emulsions for ophthalmic drug delivery was rapidly seen to offer advantages over the existing topical drug delivery vehicles [20–22].However, this drug delivery approach was not exempt of hurdles and technology challenges particularly in the formulation phase as we will see further.Author: Frederic Lallemand, Philippe Daull, Simon Benita, Ronald Buggage, Jean-Sebastien Garrigue
https://www.thefreelibrary.com/Cationic+gelatin+nanoparticles+for+drug+delivery+to+the+ocular...-a0423500194
Free Online Library: Cationic gelatin nanoparticles for drug delivery to the ocular surface: in vitro and in vivo evaluation.(Research Article) by "Journal of Nanomaterials"; Drug …
https://www.researchgate.net/publication/254860956_Cationic_submicron_emulsion_in_ocular_drug_delivery_A_Review
cationic submicron emulsion in ocular drug delivery -a review H.R. Desai, P. D. Amin Dep artment of P harmaceutical Scien ces and Technology, Institute of Chemical Technology, N.P. Marg, Matunga ...Author: Harita Desai
https://www.sciencedirect.com/science/article/pii/S1359644618305117
A variety of different DDS have been designed to enhance drug delivery to the posterior segment of the eye, including to the retinal photoreceptors (), yet the different DDS need to be tested based on the physicochemical characteristics of the drug to be delivered.Material properties will determine much of the carrier characteristics of the nanoparticle.Author: Erico Himawan, Per Ekström, Matej Buzgo, Pieter Gaillard, Einar Stefánsson, Valeria Marigo, Thorstei...
https://link.springer.com/article/10.1208%2Fs12248-010-9183-3
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
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