We have collected information about Cancer Sirna Therapy By Tumor Selective Delivery With for you. Follow the links to find out details on Cancer Sirna Therapy By Tumor Selective Delivery With.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528817/
Nov 01, 2004 · Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. ... For targeted cancer therapeutics, tumor targeting of siRNA of different sequences but virtually identical physical chemistry promises to enable inhibition of multiple tumor selective pathways in one therapeutic formulation.Author: Raymond M. Schiffelers, Aslam Ansari, Jun Xu, Qin Zhou, Qingquan Tang, Gert Storm, Grietje Molema, P...
https://academic.oup.com/nar/article/32/19/e149/1244527
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle ... Gert Storm, Grietje Molema, Patrick Y. Lu, Puthupparampil V. Scaria, Martin C. Woodle, Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle, Nucleic Acids Research, Volume 32 ...Author: Raymond M. Schiffelers, Aslam Ansari, Jun Xu, Qin Zhou, Qingquan Tang, Gert Storm, Grietje Molema, P...
https://www.ncbi.nlm.nih.gov/pubmed/15520458
Nov 01, 2004 · The results suggest achievement of two levels of targeting: tumor tissue selective delivery via the nanoparticle ligand and gene pathway selectivity via the siRNA oligonucleotide. This opens the door for better targeted therapeutics with both tissue and gene selectivity, also to improve targeted therapies with less than ideal therapeutic targets.Author: Raymond M. Schiffelers, Aslam Ansari, Jun Xu, Qin Zhou, Qingquan Tang, Gert Storm, Grietje Molema, P...
https://europepmc.org/articles/PMC528817
Nov 01, 2004 · Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle Raymond M. Schiffelers , 1, 2 Aslam Ansari , 1 Jun Xu , 1 Qin Zhou , 1 Qingquan Tang , 1 Gert Storm , 2 Grietje Molema , 3 Patrick Y. Lu , 1 Puthupparampil V. Scaria , …Author: Raymond M. Schiffelers, Aslam Ansari, Jun Xu, Qin Zhou, Qingquan Tang, Gert Storm, Grietje Molema, P...
https://www.researchgate.net/publication/8200939_Cancer_siRNA_therapy_by_tumor_selective_delivery_with_ligand-targeted_sterically_stabilized_nanoparticle
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle Article (PDF Available) in Nucleic Acids Research 32(19):e149 · February 2004 with 109 Reads
https://www.sciencedirect.com/science/article/pii/S1818087614000646
4. Potential siRNA drug delivery systems for cancer therapy. Although many strategies that can deliver siRNA into the cytoplasm of cancer cells have been reported, most of them can only satisfy in vitro applications. The majority of siRNA drugs in clinical trials are directly administered to pathology-bearing regions to avoid the complexity of ...Author: Cong-fei Xu, Jun Wang
https://www.nature.com/articles/7700931
Jan 20, 2006 · siRNA-based approaches in cancer therapy. ... with the expectation that such an approach may lead to selective and specific inhibition of tumor growth with minimal untoward side effects on normal ...Author: G R Devi
https://www.nature.com/articles/cgt201222
Thus, in contrast to conventional siRNA therapy, which solely relies on the enhanced permeability and retention effect of tumor vasculature for drug delivery, targeted therapy with this new ...Author: Haifa Shen, T. Sun, Mauro Ferrari
https://www.sciencedirect.com/science/article/pii/S0142961219302376
We demonstrate that siRNA delivery with these polymeric nanoparticles is cancer-selective, thereby avoiding potential side effects in healthy cells. We show that we can deliver siRNAs targeting several anti-GBM genes (Robo1, YAP1, NKCC1, EGFR, and survivin) simultaneously and …Author: Kristen L. Kozielski, Kristen L. Kozielski, Alejandro Ruiz-Valls, Stephany Y. Tzeng, Hugo Guerrero-C...
https://advances.sciencemag.org/content/5/9/eaaw6499.full
Sep 01, 2019 · Delivery of siRNA to specific tumor cells and tissues is necessary to limit off-target effects that could adversely affect the therapeutic index and the clinical ... The significance of the present study lies in the selective delivery of siRIPK4 to bladder tumors. ... Engineered nanoparticles for drug delivery in cancer therapy. Angew. Chem.Author: Jianye Liu, Yi Zhang, Qinghai Zeng, Hongliang Zeng, Xiaoming Liu, Pei Wu, Hongyi Xie, Leye He, Zhi L...
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