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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220359/
Lipid Molecular Shape and Membrane Stored Stress. To parameterize the concepts of lipid molecular shape, one assigns a specific packing parameter P (P = V/al, where V is the specific volume occupied by the tails, a is the area per lipid molecule in the dividing surface, and l is the effective length of the tails' region) to lipids of certain “shape” (Israelachvili 1992).Author: Vadim A. Frolov, Anna V. Shnyrova, Joshua Zimmerberg
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845970/
2.1 Fabrication of Shape and Size Specific Nanocarriers. Over the past several decades, a variety of nanoparticle carriers, synthesized using mostly “bottom-up” approaches, such as liposomal nanocarriers [7, 8], micellar formulations [], solid polymeric nanoparticles [], and polymer-drug conjugates [], have shown promising results as potential drug delivery vehicles.Author: Mary Caldorera-Moore, Nathalie Guimard, Li Shi, Krishnendu Roy
http://cshperspectives.cshlp.org/content/3/11/a004747.full
Jun 06, 2011 · With time, lipid flip-flop can diminish the area difference and the membrane shape may relax to the initial spherical configuration. Other nonlocal factors include lateral membrane tension and pressure differences between the vesicle interior and exterior.
https://www.sciencedirect.com/topics/neuroscience/naked-dna
Naked DNA refers to DNA that is not associated with proteins, lipids, or any other molecule to help protect it. Naked DNA is the result of release of genetic information into the surrounding environment, such as from bursting cells. The incoming DNA is sometimes incorporated into the bacterial genome following uptake.
https://iopscience.iop.org/article/10.1088/1361-6463/aa86e6
This provides a mechanism by which positively charged nanoparticles interact more vigorously with the lipid bilayer of the plasma membrane than negatively ... and retained a relatively circular shape for all the other ... understanding toxicity of nanomaterials in the environment as well as the development of new drug delivery vehicles. ...Author: Lu Wang, Noah Malmstadt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647019/
The delivery and uptake of lipids to the heart. ... The heart, like other tissues, can obtain more lipid than can be oxidized or stored in a non-toxic manner. It is unknown which specific lipid or array of different lipids activate processes that cause cardiac dysfunction. Pharmacologic and dietary studies that include genetic manipulation have ...Author: Konstantinos Drosatos, P. Christian Schulze
https://www.sciencedirect.com/science/article/pii/S0378517310008008
Analysis of lipid nanoparticles by Cryo-EM for characterizing siRNA delivery vehicles. ... is a leading characterization method and can reveal diversity in particle size, shape and lamellarity, however, this approach is traditionally used for qualitative review or low throughput image analysis due to inherent EM micrograph contrast ...Author: Randy Crawford, Belma Dogdas, Edward Keough, R. Matthew Haas, Wickliffe Wepukhulu, Steven Krotzer, P...
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