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https://opencommons.uconn.edu/dissertations/AAI3476640/
Biomimetic calcium phosphate (CaP) coatings improve the osteoconductivity of orthopedic implants and show promise as slow delivery systems for therapeutic proteins, therefore it is a promising approach to address the problems associated with titanium based implants.Author: Xiaohua Yu
https://www.sciencedirect.com/science/article/pii/S1359644610001534
Calcium phosphate biomaterials as bone drug delivery systems: a review ... the registration of these new systems follows a longer process than that of traditional orthopedic implants. ... et al.Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration.Author: Elise Verron, Ibrahim Khairoun, Jerome Guicheux, Jean-Michel Bouler
https://www.sciencedirect.com/science/article/pii/B9780081002872000045
4.6. CaP coating as drug delivery system. Biomimetics is a potential way to prepare surfaces that provide a favorable bone tissue response, thus enhancing the fixation between the bone and implants. The biological performance of CaP coating can be enhanced by ionic substitution/doping or substitution of strontium (Sr), silicon (Si), and silver ...Author: S. Anil, J. Venkatesan, M.S. Shim, E.P. Chalisserry, S.-K. Kim
https://infoscience.epfl.ch/record/88230/files/Bone2005.pdf
Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration B. Petera, D.P. Piolettia,*,S.LaRbb, B. Bujolib, ... Zoledronate was then grafted to hydroxyapatite (HA) coating of titanium implants. The implants were inserted in rat condyles
https://med.nyu.edu/oil/industry/technologies-licensing/devices/adherent-coatings-calcium-phosphate-phases-titanium-alloy-su
Bioactive molecules or drugs can be incorporated in the electrochemically deposited calcium phosphate, allowing their controlled release and delivery in vivo. Applications: Forming a highly adherent coating of a desired calcium phosphate phase on a titanium-based substrate for use as orthopedic …
https://www.ncbi.nlm.nih.gov/pubmed/15664002
Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration. Peter B(1), Pioletti DP, Laïb S, Bujoli B, Pilet P, Janvier P, Guicheux J, Zambelli PY, Bouler JM, Gauthier O.Author: B. Peter, Dominique P. Pioletti, S. Laib, B. Bujoli, P. Pilet, P. Janvier, J. Guicheux, P. Y. Zambel...
https://josr-online.biomedcentral.com/articles/10.1186/s13018-018-0930-y
Sep 03, 2018 · Controlled delivery system loaded with drug on the titanium implants showed the double ability of antibacterial and osteogenesis forming by biodegradable sol-gel and polymers coating [88, 89]. The controlled releasing technology of nanostructured sol-gel provided a continuous and effective local delivery system for orthopedic instruments to ...Author: Chenhao Pan, Zubin Zhou, Xiaowei Yu, Xiaowei Yu
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