Burst Release Drug Delivery Definition

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On the importance and mechanisms of burst release in ...

    https://www.sciencedirect.com/science/article/pii/S0168365901002486
    Burst release is a common phenomenon, reported in many published instances, and a selection of experimental evidence of burst release in various polymer matrix/drug systems is given in Table 3. According to the table, the burst of macromolecular agents such as proteins is frequently reported.Author: Xiao Huang, Christopher S Brazel

Drug Release - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/drug-release
    Drug release is an important property of a therapeutic system, constituting a prerequisite to absorption of the therapeutic agent and one that contributes to the rate and extent of active availability to the body.

What are the causes of burst drug release

    https://www.researchgate.net/post/what_are_the_causes_of_burst_drug_release
    burst release mechanisms depend on the nature of the drug delivery system. In short: If your system is nanoparticles burst release is due to the high specific surface that is in contact with external media or the instability of nanoparticles in the media.

Drug Release Kinetics and Transport Mechanisms of Non ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846103/
    In case studies of release kinetics, burst release is a phenomenon commonly observed in delivery devices of different forms and compositions. The burst effect may be favorable for certain indications or applications such as wound treatment, encapsulated flavors, targeted delivery and pulsatile release.Author: Yao Fu, Weiyuan John Kao

Programming Drug Delivery Kinetics for Active Burst ...

    https://pubs.acs.org/doi/full/10.1021/jacs.9b10765
    Programming Drug Delivery Kinetics for Active Burst Release with DNA Toehold Switches Mingshu Xiao Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, ChinaAuthor: Mingshu Xiao, Wei Lai, Fei Wang, Li Li, Chunhai Fan, Hao Pei

(PDF) On the importance and mechanisms of burst release in ...

    https://www.academia.edu/1062490/On_the_importance_and_mechanisms_of_burst_release_in_matrix-controlled_drug_delivery_systems
    On the importance and mechanisms of burst release in matrix-controlled drug delivery systems

Controlling Burst and Final Drug Release Times from Porous ...

    https://pubs.acs.org/doi/10.1021/bm8013632
    This work has demonstrated that it is possible to exercise a wide range of control over both the initial burst release and the final drug release times from porous polylactide (PLA) devices derived from cocontinuous polymer blends. Two strategies were used: a layer-by-layer polyelectrolyte surface deposition approach on the porous PLA surface and the application of a partially closed-cell ...Author: Zhenyu Xiang, Pierre Sarazin, Basil D. Favis

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