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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
In recent years, many such mucoadhesive drug delivery systems have been developed for oral, buccal, nasal, rectal and vaginal routes for both systemic and local effects. Dosage forms designed for mucoadhesive drug delivery should be small and flexible enough to be acceptable for patients and should not cause irritation.
https://www.researchgate.net/publication/221750117_Mucoadhesive_drug_delivery_system_An_overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
A review on bioadhesive buccal drug delivery systems: current status of formulation and evaluation methods. ... Moreover the presence of disulphide bonds may significantly alter the mechanism of drug release from the delivery system due to increase in rigidity and cross-linking.Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
https://japer.in/storage/models/article/wNpf3chMfN15jmoxMAGlq9nP2e1ZbzPjRPHnmG9j83MqvOc9538I2jYaD2DA/mucoadhesive-buccal-drug-delivery-an-overview.pdf
• The buccal mucosa is highly perfuse with blood vessels and offers a greater permeability than the skin. • A significant reduction in dose can is achieved thereby reducing dose related side effects. Limitations of Buccal Drug Delivery System [7] • Small dose of drug is required. • Drug have a …
http://www.scielo.br/pdf/bjps/v46n1/02.pdf
Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase …
https://www.imedpub.com/articles/a-comprehensive-review-on-buccal-drug-delivery-system.pdf
American Journal of Advanced Drug Delivery www.ajadd.co.uk American Journal of Advanced Drug Delivery www.ajadd.co.uk Review Article A Comprehensive Review on Buccal Drug Delivery System R. Jagadeeshwar Reddy1 , Maimuna Anjum1 and Mohammed Asif Hussain*1 Blue Birds college of Pharmacy, Bheemaram (V), Hanamkonda - 506015, Andhra Pradesh,
https://www.researchgate.net/publication/285943683_Mucoadhesive_drug_delivery_Mechanism_and_methods_of_evaluation
Conclusion: Mucoadhesive drug delivery system offer close contact with the absorption tissue, the mucous membrane, releasing the drug at the site of action leading to an increase in ...
http://www.authorstream.com/Presentation/rosecrx-1830872-mucoadhesive-drug-delivery-system/
May 27, 2013 · Mucoadhesive drug delivery system (MDDS): MDDS utilizes the property of bioahesion of certain water-soluble polymers which become adhesive on hydration and hence can be used for targeting a drug to a particular region of the body for extended periods of time. DEFINITIONS
https://journal.pda.org/content/66/5/466
Sep 01, 2012 · LAY ABSTRACT: Over the past few decades the mucoadhesive buccal drug delivery system has received a great deal of attention to develop mucoadhesive dosage forms to enable the prolonged retention at the site of action, providing a controlled release of …Author: Dattatraya Manohar Shinkar, Avinash Sridhar Dhake, Chitral Mallikarjuna Setty
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