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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848967/
Nov 05, 2019 · A number of advances in drug formulation have been made in the area of sublingual and buccal drug delivery. This review will focus on the physiological aspects that influence buccal and sublingual drug delivery and the advances in nanoparticulate drug delivery approaches for sublingual and buccal administration.Author: Susan Hua
https://www.frontiersin.org/articles/10.3389/fphar.2019.01328/full
The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required. Drugs can be rapidly and directly absorbed into the systemic circulation via venous drainage to the superior vena cava. Therefore, they are useful ...Author: Susan Hua
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771228/
Sep 24, 2019 · Buccal release belongs to the trending strategies for drugs, so we expect an increase in pharmacokinetic studies concerning NP-in-matrix buccal delivery. Nanoparticle types will probably expand too, as the actual group is mainly PLGA, nanocrystals, and some lipid particles.Author: Renata de Carvalho Feitosa, Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Juliana Souza Ri...
https://www.frontiersin.org/articles/10.3389/fphar.2019.01057/full
Buccal release belongs to the trending strategies for drugs, so we expect an increase in pharmacokinetic studies concerning NP-in-matrix buccal delivery. Nanoparticle types will probably expand too, as the actual group is mainly PLGA, nanocrystals, and some lipid particles.Author: Renata de Carvalho Feitosa, Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Juliana Souza Ri...
https://www.sciencedirect.com/science/article/pii/S1471489217300206
Buccal delivery of macromolecules (biologics) sets a great challenge for researchers. Although several niche small molecule products have been approved as simple sprays, tablets and oral films, it is not simply a case of adapting existing technologies to biologics.Author: Javier O. Morales, Javier O. Morales, David James Brayden
https://www.mdpi.com/journal/pharmaceutics/special_issues/Buccal_Delivery
This Special Issue aims to present current state-of-the-art in buccal delivery of small and large molecules focusing on physiology, pharmacology, pathology, and formulation design. We invite research scientists from the academia and pharmaceutical industry to submit original research articles or review articles.
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