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https://www.atsjournals.org/doi/abs/10.1164/ajrccm.151.6.7767526
The optimal dose and technique for administration of bronchodilators with a metered-dose inhaler (MDI) in mechanically ventilated patients have not been established. We studied the efficacy and safety of 10 puffs (90 micrograms/puff) of albuterol administered by an MDI in seven mechanically ventilated patients with chronic obstructive pulmonary disease (COPD).Author: Rajiv Dhand, A. Jubran, M. J. Tobin
https://www.ncbi.nlm.nih.gov/pubmed/7767526
Bronchodilator delivery by metered-dose inhaler in ventilator-supported patients. Dhand R(1), Jubran A, Tobin MJ. Author information: (1)Division of Pulmonary and …Author: Rajiv Dhand, A. Jubran, M. J. Tobin
https://www.monaghanmed.com/blog/dose-response-bronchodilator-delivered-metered-dose-inhaler-ventilator-supported-patients/
In non-intubated patients, metered-dose inhalers (MDIs) are accepted as the most convenient, efficient, and cost effective method of administering inhaled bronchodilators. Recent studies have demonstrated the efficacy of MDIs in ventilator-supported patients; however, the optimal dose of a bronchodilator from a MDI is unknown.
https://www.researchgate.net/publication/14445482_Dose-response_to_bronchodilator_delivered_by_metered-dose_inhaler_in_ventilator-supported_patients
In nonintubated patients, metered-dose inhalers (MDIs) are accepted as the most convenient, efficient, and cost effective method of administering inhaled bronchodilators. Recent studies have...
https://ccforum.biomedcentral.com/articles/10.1186/cc698
Jul 11, 2000 · The delivery of bronchodilators with metered-dose inhaler (MDI) in mechanically ventilated patients has attracted considerable interest in recent years. This is because the use of the MDI has several advantages over the nebulizer, such as reduced cost, ease of administration, less personnel time, reliability of dosing and a lower risk of contamination.Author: Dimitris Georgopoulos, Eleni Mouloudi, Eumorfia Kondili, Maria Klimathianaki
https://www.atsjournals.org/doi/abs/10.1164/ajrccm.154.2.8756811
Aug 01, 1996 · In nonintubated patients, metered-dose inhalers (MDIs) are accepted as the most convenient, efficient, and cost effective method of administering inhaled bronchodilators. Recent studies have demonstrated the efficacy of MDIs in ventilator-supported patients; however, the optimal dose of a bronchodilator from a MDI is unknown.Author: Rajiv Dhand, Alexander G. Duarte, Amal Jubran, John W. Jenne, James B. Fink, Patrick J. Fahey, Marti...
https://journal.chestnet.org/article/S0012-3692(15)38304-5/fulltext
The optimal method of delivering bronchodilators in mechanically ventilated patients is unclear. The purpose of this study was to compare the pulmonary bioavailability of albuterol delivered by the nebulizer, the metered-dose inhaler (MDI) and spacer, and the right-angle MDI adaptor in ventilated patients using urinary analysis of drug levels.Author: Paul Marik, John Hogan, Jim Krikorian
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150040/
Jul 11, 2000 · The delivery of bronchodilators with metered-dose inhaler (MDI) in mechanically ventilated patients has attracted considerable interest in recent years. This is because the use of the MDI has several advantages over the nebulizer, such as reduced cost, ease of administration, less personnel time, reliability of dosing and a lower risk of contamination.Author: Dimitris Georgopoulos, Eleni Mouloudi, Eumorfia Kondili, Maria Klimathianaki
https://www.reliasmedia.com/articles/103286-which-mechanically-ventilated-patients-should-receive-bronchodilators
May 01, 2007 · In these units, bronchodilators were administered by metered-dose inhaler, and the investigators determined the number of individual inhalations administered to each patient. ... Dhand R, et al. Bronchodilator delivery by metered-dose inhaler in ventilator-supported patients. Am J Respir Crit Care Med. 1995;151(6):1827-1833.
https://www.sciencedirect.com/science/article/pii/S0012369215383045
Background. The optimal method of delivering bronchodilators in mechanically ventilated patients is unclear. The purpose of this study was to compare the pulmonary bioavailability of albuterol delivered by the nebulizer, the metered-dose inhaler (MDI) and spacer, and the right-angle MDI adaptor in ventilated patients using urinary analysis of drug levels.Author: Paul Marik, John Hogan, Jim Krikorian
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