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https://www.slideshare.net/VARSHAAWASAR/brain-targeted-drug-delivery-system
Aug 04, 2014 · • Among the three main approaches to drug delivery to the CNS - systemic administration, injection into CSF pathways, and direct injection into the brain, the greatest developments is anticipated to occur in the area of targeted delivery by systemic administration.
http://www.authorstream.com/Presentation/pharma.keerthi-1606322-brain-targeting-drug-delivery-systems/
Nov 29, 2012 · Drug conjugates It involves caging compounds within glycosyl- , maltosyl, diglucosyl- and dimaltosly- derivatives of clyclodextrin. The complexes are further covalently bonded with cationic carriers and permeabilizer peptides for delivery across the BBB and with the targeting moieties for uptake by brain cells.
https://www.elsevier.com/books/brain-targeted-drug-delivery-systems/gao/978-0-12-814001-7
Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems.
http://www.authorstream.com/Presentation/herrypotter-1550273-brain-targeting-drug-delivery-system/
Sep 27, 2012 · 1 BBB- Endothelial cells + Ganglial cells = BBB Protect the brain cells from harmful substances & pathogen by preventing passage of many substances from blood into brain tissues. Only lipid soluble drugs with a molecular mass less than 600 Dalton can pass through BBB. 3.
https://www.researchgate.net/publication/279408805_Brain_targeting_Drug_Delivery_System_A_Review
The most distressing fact about delivery of drugs to the CNS is the presence of blood brain barrier that have a tendency to impair the drug distribution and denotes the major impediment for the development of CNS drugs. Neuropeptides and many drugs which are hydrophilic in nature,...
https://www.slideshare.net/ShashankSoni/brain-targeted-drug-delivery
Mar 23, 2017 · Poles apart Inimitability of Brain Targeted Drug Delivery system in Middle of NDDS. International Journal of Drug Development and Research 6 (4)15-27. 28. BBB DISRUPTION Exposure to X-irradiation and infusion of solvents such as dimethyl sulfoxide, ethanol may disrupt BBB.
https://www.slideshare.net/sayedasalma/brain-specific-delivery
Jul 24, 2018 · • Drug delivery to the brain is the process of passing therapeutically active molecules across the Blood Brain Barrier for the purpose of treating brain maladies. • This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the Blood Brain Barrier.
http://www.authorstream.com/Presentation/ishadpm-1589010-targeted-drug-delivery-system/
Nov 08, 2012 · TARGETED DRUG DELIVERY SYSTEM: A special form of drug delivery system where the pharmacologically active agent or medicament is selectively targeted or delivered only to its site of action or absorption and not to the non-target organs or tissues or …
https://www.slideshare.net/shivadheeraj/brain-targeting-14689173
Oct 11, 2012 · Gene targeting technology Craniotomy and viruses are first-generation brain gene delivery systems.Gene therapy of the brain use delivery systems that are both noninvasive and non-viral. A brain gene delivery system should enable widespread expression of atherapeutic gene throughout the brain following a simple intravenous injection.
https://www.slideshare.net/anushanagraj/targeted-drug-delivery-system
Sep 11, 2014 · STRATEGIES OF DRUG TARGETING 1) Passive Targeting : • Drug delivery systems which are targeted to systemic circulation are characterized as Passive delivery systems. • In this technique drug targeting occurs because of the body’s natural response to physicochemical characteristics of the drug or drug carrier system.
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