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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199953/
May 14, 2018 · To sum up, the healthy lifestyle helps to prevent the disease, but for treatment perspective, the IN route is a direct, potential and convenient approach to treat the brain disorders with proper clinical investigations. The direct nose-to-brain drug delivery offers a …Author: Amit Alexander, Shailendra Saraf
https://link.springer.com/book/10.1007%2F978-1-4614-9105-7
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB. It contains cutting-edge methods for studying drug delivery and administering drugs into the brain.
https://www.sciencedirect.com/science/article/pii/B9780128177785000099
The delivery of drugs using conventional dosage form such as solution or suspension via the nose-to-brain delivery has been studied in clinical trials. There is a lack of clinical trials that are focused on the nose-to-brain delivery of drug-loaded nanoparticles.Author: Amit Alexander, Mukta Agrawal, Mahavir Bhupal Chougule, Shailendra Saraf, Swarnlata Saraf
https://www.elsevier.com/books/brain-targeted-drug-delivery-systems/gao/978-0-12-814001-7
Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems.
https://www.researchgate.net/publication/336845443_Drug_Delivery_Approaches
Brain targeted Chemical Delivery Systems (CDS) have been developed to deliver drugs to the CNS in a specific and sustained manner [45,56]. This approach is based on chemicaland/or enzymatic
https://www.slideshare.net/ShashankSoni/brain-targeted-drug-delivery
Mar 23, 2017 · Brain Targeted Drug Delivery 1. APPROACH TO TARGET BRAIN DRUG DELIVERY SYSTEM SCHOLAR: MANISH KUMAR M.Pharm (Pharmaceutics) GUIDED BY: Mr. SHASHANK SONI Assistant Professor SARDAR BHAGWAN SINGH P.G. INSTITUTE OF BIO-MEDICAL SCIENCES & RESEARCH, BALAWALA, DEHRADUN, (UTTARAKHAND)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751454/
Feb 05, 2008 · Prodrug approaches are used to improve drug delivery and targeting in the CNS, and utilize passive drug uptake processes into CNS by chemically modifying a drug to become more lipophilic. Such chemical derivatives include, for example, “traditional” lipophilic esters and other lipophilic compounds that release brain-trapped intermediates, which are also referred to as chemical delivery …Author: Jarkko Rautio, Krista Laine, Mikko Gynther, Jouko Savolainen
https://www.slideshare.net/VARSHAAWASAR/brain-targeted-drug-delivery-system
Aug 04, 2014 · Brain targeted drug delivery system 1. Presented By, Varsha V. Awasarkar M Pharm 2nd Semister, (Pharmaceutics) Under the guidance of,... 2. o Aim o Introduction o Blood brain barrier • Structure of BBB • Types... 3. AIM -To emphasize on drug delivery to brain by using various approaches. 4. ...
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