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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304437/
Feb 29, 2012 · Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic delivery of a protein toxin.Author: Gregory A. Ellis, Michael J. Palte, Ronald T. Raines
https://pubs.acs.org/doi/pdf/10.1021/ja210719s
Boronate-Mediated Biologic Delivery Gregory A. Ellis,†,∥ Michael J. Palte,‡,∥ and Ronald T. Raines*,†,§ †Department of Biochemistry, ‡Medical Scientist Training Program and Molecular & Cellular Pharmacology Graduate Training Program, and §Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States *S Supporting Information
https://pubs.acs.org/doi/10.1021/ja210719s
Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic delivery …Author: Gregory A. Ellis, Michael J. Palte, Ronald T. Raines
https://pubs.acs.org/doi/full/10.1021/ja210719s
Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic delivery of a protein toxin. Thus, boronates are a noncationic carrier that can deliver a polar macromolecule into ...Author: Gregory A. Ellis, Michael J. Palte, Ronald T. Raines
https://www.ncbi.nlm.nih.gov/pubmed/22303837
Feb 29, 2012 · Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic delivery of a protein toxin.Author: Gregory A. Ellis, Michael J. Palte, Ronald T. Raines
https://www.researchgate.net/publication/221804500_Boronate-Mediated_Biologic_Delivery
Boronate-Mediated Biologic Delivery. Inefficient cellular delivery limits the landscape of macromolecular drugs. Boronic acids readily form boronate esters with the 1,2- and 1,3-diols of saccharides, such as those that coat the surface of mammalian cells. Here pendant boronic acids are shown to enhance the cytosolic delivery of a protein toxin.
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