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https://www.sciencedirect.com/science/article/pii/S0169409X11002900
Modern methods for delivery of drugs across the blood–brain barrier ... The blood–brain barrier (BBB) is a dynamic barrier protecting the brain against invading organisms and unwanted substances. It is also the most important barrier impeding drug transport into the brain via the blood circulation. Despite the rapid development in our ...Author: Yan Chen, Lihong Liu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494002/
Aug 29, 2012 · Introduction. The blood–brain barrier (BBB) prevents entry into the brain of most drugs from the blood. The presence of the BBB makes difficult the development of new treatments of brain diseases, or new radiopharmaceuticals for neuroimaging of brain.Author: William M Pardridge
https://www.ncbi.nlm.nih.gov/pubmed/27020469
Author information: (1)a Brain Research Institute , University of California , Los Angeles , CA , USA. INTRODUCTION: There are 2 misconceptions about the cerebrospinal fluid (CSF), the blood-brain barrier (BBB), and brain drug delivery, which date back to the discovery of a barrier between blood and brain over 100 years ago.Author: William M. Pardridge
https://www.drugtargetreview.com/news/36234/deliver-blood-brain/
Oct 19, 2018 · The team believe that this method could be used to deliver larger molecules deep into brain tissue, and could be used in brain diseases as a way to overcome the issue of delivering drugs through the blood-brain barrier. The study was published in the journal JCI Insight.
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