Biodegradable Polymers Used In Drug Delivery System

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Polymers for Drug Delivery Systems - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
    POLYMER THERAPEUTICS FOR DRUG DELIVERY. Polymer therapeutics is a term used to describe an increasingly important area of biopaharmaceutics in which a linear or branched polymer chain behaves either as the bioactive (a polymeric drug) or, more commonly, as the inert carrier to which a therapeutic is covalently linked, as in the case of polymer-drug conjugates, polymer-protein conjugates, polymeric micelles…Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas

BIODEGRADABLE POLYMERS AND THEIR ROLE IN DRUG DELIVERY ...

    https://www.pharmatutor.org/articles/biodegradable-polymers-role-drug-delivery
    The use of biodegradable polymer in drug delivery grew from the search for polymers that could be employed as degradable sutures. Synthetic polymers such as poly (glycolic acid) were first developed in the 1950is and their poor hydrolytic stability made …

Biodegradable polymers for drug delivery systems ...

    https://www.sciencedirect.com/science/article/pii/B9781845690700500047
    A defining therapeutic feature of a biodegradable polymer used in modern drug delivery is facile degradation into oligomers or monomers with concomitant kinetically controlled-drug-release profiles. Biodegradable drug carriers are responsible for delivering drugs and then typically degrading through hydrolysis or common proteases for physiological clearance.Author: G. S. Kwon, D. Y. Furgeson

Biodegradable Polymers and their Role in Drug Delivery ...

    https://biomedres.us/fulltexts/BJSTR.MS.ID.002056.php
    Many biodegradable polymers have been investigated for use in drug delivery and have established a role in controlled drug release. Aliphatic polyesters such as poly(lactic acid), poly(glycolic acid), poly(lactide-co-glycolide), poly(decalactone) and poly(εcaprolactone) have been the subject of the most extensive investigations.Author: Kiran Dhaliwal, Priya Dosanjh, Jose Sanchez Payá

Biodegradable Polymers as Drug Delivery Systems

    https://www.researchgate.net/publication/279724491_Biodegradable_Polymers_as_Drug_Delivery_Systems
    Although a variety of polymeric materials are available to serve as a release retarding microencapsulating agent but use of natural biodegradable polymers to prolong the delivery of the drugs …

Biodegradable block copolymers as injectable drug-delivery ...

    https://www.nature.com/articles/42218
    Aug 28, 1997 · Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require complicated fabrication processes using organic...Author: Byeongmoon Jeong, You Han Bae, Doo Sung Lee, Sung Wan Kim

Biodegradable polymers in controlled drug delivery.

    https://www.ncbi.nlm.nih.gov/pubmed/6400195
    The use of biodegradable systems for the sustained release of fertility-regulating agents is based on type III erosion. Polymer erosion tends to lead drug release, and there is some indication that drug release from the implant is controlled by rate of solubilization of the highly water-insoluble steroid.Author: Heller J

Polymers in Controlled Drug Delivery MDDI Online

    https://www.mddionline.com/polymers-controlled-drug-delivery
    Work with biodegradable polymers has also yielded polyorthoesters that are pH sensitive and that will degrade more quickly in acidic environments. 3 Such polymers have been studied as the central core of a drug delivery system in which the polymer-insulin matrix is surrounded by a membrane containing grafted glucose oxidase, which provides the reaction substrate and the change in pH necessary to enhance biodegradation and subsequent insulin delivery.

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