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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
POLYMER THERAPEUTICS FOR DRUG DELIVERY. Polymer therapeutics is a term used to describe an increasingly important area of biopaharmaceutics in which a linear or branched polymer chain behaves either as the bioactive (a polymeric drug) or, more commonly, as the inert carrier to which a therapeutic is covalently linked, as in the case of polymer-drug conjugates, polymer-protein conjugates, polymeric micelles…Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.pharmatutor.org/articles/biodegradable-polymers-role-drug-delivery
HISTORY : The use of biodegradable polymer in drug delivery grew from the search for polymers that could be employed as degradable sutures. Synthetic polymers such as poly (glycolic acid) were first developed in the 1950is and their poor hydrolytic stability made them unsuitable for …
https://www.sciencedirect.com/science/article/pii/S0168365999001340
Both types of biodegradable polyesters seem to be promising candidates for parenteral protein delivery systems, allowing a synchronization of both pore diffusion and polymer erosion for the controlled release of hydrophilic drug candidates. 2.Author: Armin Breitenbach, You Xin Li, Thomas Kissel
https://www.pharmatutor.org/articles/review-parenteral-controlled-drug-delivery-system
Biodegradable polymers investigated for controlled drug delivery are Poly lactide / poly glycolide polymers, Poly anhydrides, Poly caprolactone, Poly orthoesters, Psuedo polyamino acid, Poly phosphazenes, Natural polymers. Desirable characteristics of an ideal Parenteral drug carrier. Versatility in that carrier can deliver a variety of agents.
https://healthcare.evonik.com/product/health-care/en/products/biomaterials/resomer/pages/controlled-release.aspx
The RESOMER® catalog represents the industry’s most broad, versatile and trusted portfolio of biodegradable polymers for controlled release. All polymers have a strong record for safety and improving targeting and precise delivery timing for complex parenteral drug products. Degradation rates, stability and all key polymer properties have been thoroughly studied over more than three …
https://link.springer.com/chapter/10.1007%2F978-1-4614-0881-9_5
Sep 27, 2011 · Tsung J., Burgess D.J. (2012) Biodegradable Polymers in Drug Delivery Systems. In: Siepmann J., Siegel R., Rathbone M. (eds) Fundamentals and Applications of Controlled Release Drug Delivery. Advances in Delivery Science and Technology.Author: Jamie Tsung, Diane J. Burgess
https://www.sciencedirect.com/science/article/pii/S0014305719305920
Biodegradable polymers undergo biodegradation in vivo either enzymatically or non-enzymatically and yield biocompatible or harmless by-products .These polymers have been reported to improve drug pharmacokinetics and reduce the side effects .Recent breakthrough in controlled drug delivery system (CDDS), sustained release drug delivery system (SRDDS), vaccine, nucleic acid, protein, and ...Author: Shiv Kumar Prajapati, Ankit Jain, Aakanchha Jain, Sourabh Jain
https://www.researchgate.net/publication/279724491_Biodegradable_Polymers_as_Drug_Delivery_Systems
Although a variety of polymeric materials are available to serve as a release retarding microencapsulating agent but use of natural biodegradable polymers to prolong the delivery of the drugs is ...
https://www.mddionline.com/polymers-controlled-drug-delivery
Figure 1. Drug levels in the blood with (a) traditional drug dosing and (b) controlled-delivery dosing. In recent years, controlled drug delivery formulations and the polymers used in these systems have become much more sophisticated, with the ability to do more than simply extend the effective release period for a particular drug.
https://www.ncbi.nlm.nih.gov/pubmed/8521523
Biodegradable microspheres in drug delivery. ... characteristics of biodegradable polymers (physicochemical properties, bioerosion mechanism, biocompatibility), preparation method for the microspheres, drug release from parenteral products and briefly nonparenteral products. The relationship between release pattern and pharmacological activity ...Author: Hiroaki Okada, Hajime Toguchi
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