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https://www.nature.com/articles/42218
Aug 28, 1997 · Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require …Author: Byeongmoon Jeong, You Han Bae, Doo Sung Lee, Sung Wan Kim
http://adsabs.harvard.edu/abs/1997Natur.388..860J
Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require complicated fabrication processes using organic solvents. Such systems have the disadvantage that the use of organic solvents can cause denaturation when protein drugs are to be encapsulated.
https://www.sciencedirect.com/science/article/pii/B978012817909300011X
Biodegradable Block Copolymers as Injectable Drug Delivery Systems Various types of stimuli-sensitive polymeric materials have been used for the injectable preparations. The polymers (such as poloxamers or isopropyl acrylamide) that exhibit some responses to stimuli like, temperature, electric field, or pH, have applicability for injectable systems.Author: Vandana Soni, Vikas Pandey, Saket Asati, Vishal Gour, Rakesh K. Tekade
https://www.sciencedirect.com/science/article/pii/S0168365999000619
The use of these two biodegradable polymers have great advantages for sustained injectable drug delivery systems. The formulation is simple, which is totally free of organic solvent. In sol or aqueous solution state of this polymer solubilized hydrophobic drugs prior to form gel matrix.Author: B. Jeong, Y.K. Choi, Y.H. Bae, G. Zentner, S.W. Kim
https://www.sciencedirect.com/science/article/abs/pii/S0168365999000619
The use of these two biodegradable polymers have great advantages for sustained injectable drug delivery systems. The formulation is simple, which is totally free of organic solvent. In sol or aqueous solution state of this polymer solubilized hydrophobic drugs prior to form gel matrix.Author: B. Jeong, Y.K. Choi, Y.H. Bae, G. Zentner, S.W. Kim
https://www.sciencedirect.com/science/article/pii/S0168365901002760
May 14, 2001 · ReGel ® has been developed as a biodegradable drug delivery system that is injected as a liquid, thereafter forming a gel in response to body temperature. The gel forms a controlled release drug depot with delivery times ranging from 1 to 6 weeks.Author: Gaylen M. Zentner, Ramesh Rathi, Chung Shih, James C. McRea, Min Hyo Seo, Hunseung Oh, B. G. Rhee, J...
https://link.springer.com/chapter/10.1007%2F978-1-4614-0881-9_5
Sep 27, 2011 · This chapter is focused on the use of biodegradable polymers in long acting injectable drug delivery systems with an emphasis on marketed products. An overview is provided of how the chemical structures and physical properties of these polymers impact functionality of drug delivery systems and how to strategically select polymers for different ...Author: Jamie Tsung, Diane J. Burgess
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