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https://www.ncbi.nlm.nih.gov/pubmed/7348718
Biocompatibility of polymeric delivery systems for macromolecules. Langer R, Brem H, Tapper D. We previously reported the use of polymeric delivery systems capable of sustained release of substances with molecular weights up to 2 X 10(6).Author: Robert Langer, Henry Brem, David Tapper
https://onlinelibrary.wiley.com/doi/abs/10.1002/jbm.820150212
Biocompatibility of polymeric delivery systems for macromolecules Robert Langer Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, and the Department of Surgery, Children's Hospital Medical Center…Author: Robert Langer, Henry Brem, David Tapper
https://www.deepdyve.com/lp/wiley/biocompatibility-of-polymeric-delivery-systems-for-macromolecules-sNhMTSoqVJ
Biocompatibility of polymeric delivery systems for macromolecules The current study examined the tissue compatibilities of these slow‐release agents and of other polymeric materials. To observe in vivo host responses to specific implants, tests were conducted in the rabbit cornea.
https://www.sciencedirect.com/science/article/pii/026766059390104F
Ocular and brain biocompatibility of polymeric delivery materials Fig. 4. 1Vficrophotograph of rat brain 6 days after surgical implantation of the polymer HYAFF 7. The implant is surrounded by a localized reaction characterized by a small rim of necrosis, histiocytic infiltrates and edema.Author: Alessandro Olivi, K. D. Kim, L. Benedetti, Jonathan Ira Epstein, M. L. Pinn, L. Callegaro, Henry Bre...
https://link.springer.com/chapter/10.1007/978-1-4684-9001-5_15
In this paper we review two areas of our research 1) systems that release large molecules through porous polymer matrices and 2) modulated controlled release polymer systems. This is a preview of subscription content, log in to check access.Author: Robert Langer
https://www.cd-bioparticles.net/polymeric-nanoparticles-production
Introduction to Polymeric Nanoparticles . Polymer is a class of natural or synthetic substances composed of macromolecules that are multiples of monomers. Polymeric nanoparticles are manipulatable materials and have the potential of reabsorption in the body.
https://www.sciencedirect.com/book/9780081017500/engineering-of-biomaterials-for-drug-delivery-systems
Biopolymers have attracted considerable interest for the development of drug delivery systems (DDSs) owing to their biocompatibility, nontoxicity, renewability, and mild processing conditions. These polymers are degradable in vivo, either enzymatically or nonenzymatically, and can be metabolized and excreted via normal physiological pathways.
https://onlinelibrary.wiley.com/doi/abs/10.1002/jps.2600690305
Matrixes composed of ethylene–vinyl acetate copolymer are useful vehicles for the sustained release of macromolecules such as proteins. A new procedure for fabricating these polymeric delivery systems involved mixing the dry, powdered macromolecule with a polymer …Author: William D. Rhine, Dean S.T. Hsieh, Robert Langer
https://www.researchgate.net/publication/230846995_Polymer_biocompatibility
Polymer Biocompatibility 49 Biocompatibility is a term that encompasses many aspects of the material, including its physical, mechanical, and chemical properties, as well as potential cytotoxic ...
https://pubs.acs.org/doi/10.1021/acs.macromol.7b02637
Environmental stimuli-responsive nucleobase-functionalized supramolecular polymers, a combination of oligomeric polypropylene glycol segments as a thermosensitive element and hydrogen-bonded uracil as a photosensitive moiety, were successfully developed and undergo spontaneous self-assembly to form uniform nanosized micelles via self-complementary ...Author: Belete Tewabe Gebeyehu, Shan You Huang, Ai Wei Lee, Jem Kun Chen, Juin Yih Lai, Juin Yih Lai, Duu Jo...
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