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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952648/
Aug 16, 2010 · Finally, the drug-delivery capability of MSNs is demonstrated by following tumor growth in mice treated with camptothecin-loaded MSNs. These results indicate that MSNs are biocompatible, preferentially accumulate in tumors, and effectively deliver drugs …Author: Jie Lu, Monty Liong, Zongxi Li, Jeffrey I. Zink, Fuyuhiko Tamanoi
https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201000538
Finally, the drug‐delivery capability of MSNs is demonstrated by following tumor growth in mice treated with camptothecin‐loaded MSNs. These results indicate that MSNs are biocompatible, preferentially accumulate in tumors, and effectively deliver drugs to the tumors and suppress tumor growth.Author: Jie Lu, Monty Liong, Zongxi Li, Jeffrey I. Zink, Fuyuhiko Tamanoi
https://www.researchgate.net/publication/45152490_Biocompatibility_Biodistribution_and_Drug-Delivery_Efficiency_of_Mesoporous_Silica_Nanoparticles_for_Cancer_Therapy_in_Animals
Biocompatibility, Biodistribution, and Drug‐Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals
https://www.sciencedirect.com/science/article/pii/S0168365915005672
Despite the interest in developing albumin nanoparticles for pulmonary drug delivery, information on the safety, clearance kinetics, and biodistribution of the albumin vehicle is currently lacking.Author: A. Woods, A. Patel, D. Spina, Y. Riffo-Vasquez, A. Babin-Morgan, R.T.M. de Rosales, K. Sunassee, S. ...
https://www.researchgate.net/publication/250868192_Biocompatibility_and_drug_delivery_systems
Drug delivery technology has emerged as an important focus of biotechnological research and commercial enterprise. While much attention is justifiably focused on the design and effectiveness of drug delivery devices, the nature of their interaction with surrounding tissues – their biocompatibility …
https://www.europepmc.org/articles/PMC4441346/
Biodistribution and delivery efficiency of unmodified tumor-derived exosomes. Find the latest peer-reviewed research articles and preprints on Coronavirus here. Feedback Complete survey. Sign in or ...
https://portal.nifa.usda.gov/web/crisprojectpages/1008246-bio-based-polymeric-strategies-for-improved-cancer-drug-delivery.html
Drug delivery systems can be used to increase a drug's circulatory stability and thereby raise theprobability for passive accumulation within regions of enhanced permeability, particularly tumor tissue.As a result, exposure of healthy tissue to associated therapeutics is limited, while therapeutic efficacy ismaximized. Both the specificity and therapeutic efficacy of drug delivery systems can ...
https://www.intechopen.com/books/advanced-technology-for-delivering-therapeutics/introductory-chapter-drug-delivery-concepts
However, controlled release systems do not exclusively deliver the drug to the target organ. For this reason, the target-specific drug delivery systems must be designed in order to control biodistribution of the drug. Consequently, various novel concepts have been emerged to meet the specific needs of an ideal drug delivery system.Author: Sabyasachi Maiti, Kalyan Kumar Sen
https://www.sciencedirect.com/science/article/pii/S1742706116305931
The shape effect of M-MSNPs has been observed mostly in vitro and therefore await further validation in vivo. It is well known that tumor accumulation and biodistribution are two important factors determining efficacy and safety during nanoparticle-mediated drug delivery to solid tumor [50].Author: Dan Shao, Meng-meng Lu, Ya-wei Zhao, Fan Zhang, Yong-fei Tan, Xiao Zheng, Yue Pan, Xuan-ang Xiao, Zh...
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