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https://www.sciencedirect.com/science/article/pii/B9780128097175000129
Bioadhesive drug delivery systems can be delivered through various routes like oral, nasal, ocular, and vaginal. The main components of bioadhesive drug delivery systems are bioadhesive polymers, which may be natural or synthetic in nature.Author: Lalit Kumar, Shivani Verma, Bhuvaneshwar Vaidya, Vivek Gupta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Gastrointestinal Mucoadhesive Drug Delivery Systems. Oral route is undoubtedly most favored route of administration, but hepatic first-pass metabolism, degradation of drug during absorption, mucus covering GI epithilia, and high turnover of mucus are serious concerns of oral route.
https://www.ncbi.nlm.nih.gov/pubmed/3998999
Bioadhesive polymers as platforms for oral controlled drug delivery II: synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers. Ch'ng HS, Park H, Kelly P, Robinson JR.Author: Hung Seng Ch'Ng, Haesun Park, Peggy Kelly, Joseph R. Robinson, Joseph R. Robinson
https://www.researchgate.net/publication/317637304_Bioadhesive_drug_delivery_systems_Overview_and_recent_advances
This review provides an overview of the understanding of bioadhesive drug delivery system along with the recent advances in their formulation development. ... polymers have optimal pola rity ...Author: Devarshi Brahmbhatt
http://www.ijpmbs.com/uploadfile/2015/0412/20150412031556858.pdf
RECENT ADVANCES IN MUCOADHESIVE/ BIOADHESIVE DRUG DELIVERY SYSTEM: A REVIEW Phanindra B1*, B Krishna Moorthy1 and M Muthukumaran1 Review Article The current article has been focused on the mucoadhesive drug delivery system may be designed to enable prolonged retention at the site of application, providing a controlled rate of drug release
http://www.bioline.org.br/pdf?pr10012
with introduction of bioadhesion with theories and mechanism, history, different bioadhesive polymers, characteristics of desired bioadhesive polymers, this article then proceeds to cover the various sites suitable for mucoadhesive drug delivery system followed by the factors affecting bio/ mucoadhesion.
https://www.sciencedirect.com/science/article/abs/pii/S0169409X05001444
This review highlights the use of mucoadhesive polymers in buccal drug delivery. Starting with a review of the oral mucosa, mechanism of drug permeation, and characteristics of the desired polymers, this article then proceeds to cover the theories behind the adhesion of bioadhesive polymers to …Author: Nazila Salamat-Miller, Montakarn Chittchang, Thomas P. Johnston
https://www.researchgate.net/publication/43561170_Bioadhesive_Polymeric_Platforms_for_Transmucosal_Drug_Delivery_Systems_-_a_Review
Consequently, bioadhesive polymers ha ve extensively been employed in transmucosal drug delivery systems. If these materials are then incorporated into pharmaceutical formulations, drug absorption by
https://www.slideshare.net/shreeraj9183/bioadhesive-drug-delivery-system
Oct 22, 2012 · Bioadhesive drug delivery system ... This fiber is intended to be placed in the buccal cavity for oral mucosal drug delivery The fiber may also prepare for periodontal application ... mucociliary clearance affects the retention and therefore the effects of the drugs in the nose. The effects of bioadhesive polymers on mucociliary clearance was ...
https://www.slideshare.net/boreddysunilkumarreddy/bioadhesive-drug-delivery-system-26809968
Oct 02, 2013 · The buccal mucosa is less permeable compared to other oral drug delivery systems and is unable to retain dosage forms at the site of absorption. The use of bioadhesive polymers in buccal drug delivery systems allows a better retention of a dosage form by spreading it over the absorption site.
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