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https://rd.springer.com/article/10.1007/s11095-004-1183-5
Bioadhesive dosage forms that adhere to the esophageal mucosa and prolong contact have been investigated to improve the efficacy of locally acting agents. The rationale for local esophageal drug delivery and its limitations, the factors that determine adhesion to this organ, and the experimental models used in esophageal drug delivery research are reviewed.Author: Hannah Batchelor
https://www.researchgate.net/publication/7952191_Bioadhesive_Dosage_Forms_for_Esophageal_Drug_Delivery
Mucoadhesive materials are widely used to develop dosage forms for transmucosal drug delivery via ocular, nasal, esophageal, oral, vaginal, rectal, and intravesical routes of administration.Author: Hannah Batchelor
https://www.deepdyve.com/lp/springer-journals/bioadhesive-dosage-forms-for-esophageal-drug-delivery-2JHW9UM0EJ
Feb 24, 2005 · Bioadhesive Dosage Forms for Esophageal Drug Delivery The low permeability and transient nature of the esophagus means that it is unsuitable for delivery of drugs for systemic action. However, esophageal disorders including fungal infection, cancers, motility dysfunction, and damage due to gastric reflux may be treated using locally acting agents that offer benefits of reduced dosage …Author: Batchelor, Hannah
http://www.ijpmbs.com/uploadfile/2015/0412/20150412031556858.pdf
For drug delivery purposes, the term bioadhesion implies attachment of a drug carrier system to a specified biological location. The biological surface can be epithelial tissue or the mucus coat on the surface of a tissue. If adhesive attachment is to a mucus coat, the …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
Tablets have been the most commonly investigated dosage forms for buccal drug delivery. Several bioadhesive buccal tablet formulations have been developed by direct compression method in recent years either for local or systemic drug delivery.Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
https://www.sciencedirect.com/science/article/pii/B9780128097175000129
Bioadhesive drug delivery systems can be delivered through various routes like oral, nasal, ocular, and vaginal. The main components of bioadhesive drug delivery systems are bioadhesive polymers, which may be natural or synthetic in nature.Author: Lalit Kumar, Shivani Verma, Bhuvaneshwar Vaidya, Vivek Gupta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387832/
Jun 11, 2012 · The esophagus is an organ of transport with a very short transit time that does not favor drug contact or delivery. Several pharmaceutical studies have been carried out to investigate bioadhesive dosage forms that adhere to esophageal mucosa and prolong contact.Author: Massimo P Di Simone, Fabio Baldi, Valentina Vasina, Fabrizio Scorrano, Maria Laura Bacci, Antonella ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Dosage forms designed for mucoadhesive drug delivery should be small and flexible enough to be acceptable for patients and should not cause irritation. Other desired characteristics of a mucoadhesive dosage form include high drug loading capacity, controlled drug release (preferably unidirectional release), good mucoadhesive properties, smooth surface, tastelessness, and convenient application.
https://www.researchgate.net/publication/317637304_Bioadhesive_drug_delivery_systems_Overview_and_recent_advances
This review provides an overview of the understanding of bioadhesive drug delivery system along with the recent advances in their formulation development. ... the Bioadhesive Dosage form will ...Author: Devarshi Brahmbhatt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention. Mucoadhesive dosage forms may be designed to enable ...
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