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https://www.researchgate.net/publication/47642636_Bioadhesive_delivery_systems_for_mucosal_vaccine_delivery
To improve mucosal vaccine delivery, the use of bioadhesive delivery systems offers numerous advantages, including protection from degradation, increasing concentration of antigen in the vicinity ...
https://www.tandfonline.com/doi/abs/10.3109/1061186X.2010.529143
Oct 18, 2017 · To improve mucosal vaccine delivery, the use of bioadhesive delivery systems offers numerous advantages, including protection from degradation, increasing concentration of antigen in the vicinity of mucosal tissue for better absorption, extending their residence time, and/or targeting them to sites of antigen uptake.Author: Barbara C. Baudner, Derek T. O’Hagan
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Mucoadhesive drug delivery systems in the past have been formulated as powders, compacts, sprays, semisolids, or films. For example, compacts have been used for drug delivery to the oral cavity,[ 51 ] and powders and nanoparticles have been used to facilitate drug administration to the nasal mucosa.[ 52 , 53 ] Recently oral strips[ 54 ] were developed for tongue or buccal cavity.
https://www.sciencedirect.com/science/article/pii/S0168365900003308
In the current studies, we report the use of an influenza hemagglutinin (HA) vaccine administered IN to mice, rabbits and micro-pigs along with LT mutants and a bioadhesive delivery system, comprising HYAFF microspheres. The IN route has been used previously to administer vaccines and adjuvants to animal models [8].Author: Manmohan Singh, Maylene Briones, Derek T. O’Hagan
https://www.amazon.com/Bioadhesive-Drug-Delivery-Systems-Pharmaceutical/dp/0824719956
examines bioadhesive carriers, diffusion or penetration enhancers, and lectin-targeted vehicles describes vaginal, nasal, buccal, ocular, and transdermal drug delivery reviews bioadhesive interactions with the mucosal tissues of the eye and mouth, and those in the respiratory, urinary, and gastrointestinal tractsPrice: $52.47
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
To fulfill the therapeutic requirements, formulations for buccal administration should contain: mucoadhesive agents, to maintain an intimate and prolonged contact of the formulation with the absorption site; penetration enhancers, to improve drug permeation across mucosa (transmucosal delivery) or into deepest layers of the epithelium (mucosal delivery), enzyme inhibitors, to protect the drug from the degradation by means of mucosal enzymes …Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
https://www.researchgate.net/publication/317637304_Bioadhesive_drug_delivery_systems_Overview_and_recent_advances
Bio adhesive systems have gained growing interest due to its ability to localize the drug delivery along with sustained release. This leads to reduction of side-effects due to non-specific targeting. This review provides an overview of the understanding of bioadhesive drug delivery...Author: Devarshi Brahmbhatt
https://link.springer.com/article/10.1007/s13233-019-7042-3
May 09, 2019 · Efficient Mucosal Immunization by Mucoadhesive and pH-Sensitive Polymeric Vaccine Delivery System 1. State Key Laboratory of Natural Medicines, Department of PharmaceuticsChina Pharmaceutical... 2. Jiangsu Key Laboratory of Druggability of BiopharmaceuticalsChina Pharmaceutical... 3. Jiangsu Key ...Author: Lei Xing, Tian-Jiao Zhou, Ya-Tong Fan, Yu-jing He, Tao Pang, Ki-Hyun Cho, Jin-Jian Lu, Hu-Lin Jiang,...
https://www.slideshare.net/shreeraj9183/bioadhesive-drug-delivery-system
Oct 22, 2012 · Chewing gums are mobile drug delivery systems The main target mucosa for drug absorption is sublingual mucosa Drug release is generally rapid but not as immediate as in case of fast dissolving tablets Commercially available medicated chewing gums are currently available for pain relief, smoking cessation, travel illness, and freshening of breath Medicated chewing gum offers advantages in comparison to conventional oral mucosal …
https://www.sciencedirect.com/science/article/pii/S1773224705500534
Mucosal delivery of diphtheria toxoid using polymer-coated-bioadhesive liposomes as vaccine carriers C. Martin, S. Somavarapu, H.O. Alpar, * [email protected] Vaccine Delivery Group, Centre for Drug Delivery Research, University of London, School of Pharmacy, 29–39, Brunswick Square, London, WC1N 1AX, United Kingdom Vaccine Delivery Group, Centre for Drug Delivery Research, University of London, …Author: C. Martin, S. Somavarapu, H.O. Alpar
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