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https://www.researchgate.net/publication/41423043_b-Cyclodextrin-centered_star-shaped_amphiphilic_polymers_for_doxorubicin_delivery
Delivery of doxorubicin could be achieved by a novel micellar system based on beta-cyclodextrin-centered star-shaped amphiphilic polymers (sPEL/CD).
https://www.sciencedirect.com/science/article/pii/S0142961215003129
The reported star-shaped polymer could form stable micelles in aqueous solutions even in the presence of serum. In addition, anti-cancer drug doxorubicin and tumor-suppressing p53 gene were loaded in the process of micelle formation. The formed polyplex was biocompatible and highly efficient for both drug and gene delivery.Author: Yongmao Li, Bing Xu, Tao Bai, Wenguang Liu
https://www.sciencedirect.com/science/article/pii/S0927776518302777
A series of star-shaped polymers CD-g-TPGS with different TPGS substitution degree were synthesized for doxorubicin (DOX) delivery, where β-CD was identified as a core and TPGS as branches. These star polymers can self-assemble into nanoparticles with DOX.Author: Conglian Yang, Yuting Qin, Kun Tu, Chenfeng Xu, Zhen Li, Zhiping Zhang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637021/
Oct 25, 2015 · A Comprehensive Review on Cyclodextrin-Based Carriers for Delivery of Chemotherapeutic Cytotoxic Anticancer Drugs. Bina Gidwani and Amber Vyas * ... trimers, and polymers, incorporated as amphiphilic molecules and forms aggregate. ... Deng et al. 2011 synthesized star-shaped polymers for sustained delivery of methotrexate. This polymer ...Author: Bina Gidwani, Amber Vyas
https://pubs.acs.org/doi/abs/10.1021/acs.biomac.5b01676
To date, improving oral bioavailability of water-soluble drugs with poor membrane permeability is still challenging. An example of this includes doxorubicin hydrochloride (DOX·HCl), a widely used chemotherapeutic. We therefore developed a novel DOX·HCl-loaded polymersome (Ps-DOX·HCl) self-assembled by amphiphilic β-cyclodextrin-centered triarm star polymer (mPEG2k-PLA3k)3-CD with …Author: Mengying Hu, Yurun Shen, Lu Zhang, Liyan Qiu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445873/
Doxorubicin-loaded aromatic imine-contained amphiphilic branched star polymer micelles: synthesis, self-assembly, and drug delivery Liang Qiu , Chun-Yan Hong , and Cai-Yuan Pan Chinese Academy of Sciences Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei ...Author: Liang Qiu, Chun-Yan Hong, Cai-Yuan Pan
https://www.mdpi.com/2079-4991/9/4/547/pdf
In recent years, polymer micelles in nano drug delivery systems have attracted much attention in the chemotherapy of cancer [1,2]. Polymers with highly branched, complex topologies (such as dendritic, hyperbranched, multi-arm star-shaped, and brush copolymers) usually have uniqueAuthor: Meng Li, Jian-Wei Guo, Wei-Qiu Wen, Jem-Kun Chen
https://pubs.acs.org/doi/full/10.1021/ja207150n
Efficient delivery of therapeutics into tumor cells to increase the intracellular drug concentration is a major challenge for cancer therapy due to drug resistance and inefficient cellular uptake. Herein, we have designed a tailor-made dual pH-sensitive polymer–drug conjugate nanoparticulate system to overcome the challenges. The nanoparticle is capable of reversing its surface charge from ...Author: Jin-Zhi Du, Xiao-Jiao Du, Cheng-Qiong Mao, Jun Wang
https://www.researchgate.net/publication/23683304_Doxorubicin-Loaded_Polymeric_Micelles_Based_on_Amphiphilic_Polyphosphazenes_with_PolyN-isopropylacrylamide-co-NN-dimethylacrylamide_and_Ethyl_Glycinate_as_Side_Groups_Synthesis_Preparation_and_In_Vitr
Delivery of doxorubicin could be achieved by a novel micellar system based on beta-cyclodextrin-centered star-shaped amphiphilic polymers (sPEL/CD).
https://onlinelibrary.wiley.com/doi/full/10.1002/app.33459
Current and potential applications of amphiphilic polymers include stabilizers, dispersants, emulsifiers, wetting agents, and nanoreservoirs. 1, 2 In biomedical fields, amphiphilic polymers have been drawing significant attention as promising carriers in drug delivery and matrices in tissue engineering. 3-5 The aims of utilizing the polymeric ...Author: Hongxia Gao, Mingjun Li, Yan Wu
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