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https://www.researchgate.net/publication/5507102_Barriers_to_Glaucoma_Drug_Delivery
Topical medications remain the mainstay of glaucoma treatment. This review will aim to cover the pharmacokinetics of topically applied drops, the ocular barriers to drug delivery, and the role of ...
https://nebraska.pure.elsevier.com/en/publications/barriers-to-glaucoma-drug-delivery
Topical medications remain the mainstay of glaucoma treatment. This review will aim to cover the pharmacokinetics of topically applied drops, the ocular barriers to drug delivery, and the role of ophthalmic drug formulation in enhancing drug delivery to the target tissue while minimizing side effects and increasing patient compliance.Author: Deepta Ghate, Henry F. Edelhauser
https://journals.lww.com/glaucomajournal/Abstract/2008/03000/Barriers_to_Glaucoma_Drug_Delivery.11.aspx
Topical medications remain the mainstay of glaucoma treatment. This review will aim to cover the pharmacokinetics of topically applied drops, the ocular barriers to drug delivery, and the role of ophthalmic drug formulation in enhancing drug delivery to the target tissue while minimizing side effects and increasing patient compliance.
https://www.glaucoma.org/treatment/new-medication-delivery-systems-for-glaucoma.php
Thus, the barriers to continuing regular medical treatment in patients with glaucoma may be quite significant. A published study identified 71 different obstacles to medication adherence in patients with glaucoma. For these reasons, new medication delivery systems for glaucoma would be a welcome addition to our treatment options.
https://www.sciencedirect.com/science/article/pii/S0142961220302076
Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: A push beyond the limits of static and dynamic ocular barriers toward glaucoma therapy. Author links open overlay panel Li-Jyuan Luo a 1 Duc Dung Nguyen a 1 Jui-Yang Lai a b c. Show more.Author: Li-Jyuan Luo, Duc Dung Nguyen, Jui-Yang Lai
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171267/
Apr 08, 2011 · Drug delivery systems have the potential to improve patient adherence, reduce side effects, increase efficacy, and ultimately, preserve sight for glaucoma patients. In this review, we discuss benefits and limitations of the current systems of delivery and application, as well as those on the horizon.Author: Erin Baker Lavik, M. H. Kuehn, Y. H. Kwon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.glaucoma.org/treatment/alternative-drug-delivery-systems-for-glaucoma.php
New and novel proposals for glaucoma drug delivery were the topic of a session at the Glaucoma 360 New Horizons Forum in San Francisco (presented by Glaucoma Research Foundation). The session highlighted a variety of amazing new technologies that we hope will soon become available to improve the medical therapy of glaucoma.
https://www.wjgnet.com/2220-3192/full/v2/i4/78.htm
Drug delivery through topical or systemic route faces a number of challenges limiting their success. Advancements in drug design, drug formulation and devices have led to successful products. But the scientists have experimented with alternate routes of drug delivery that can overcome barriers presented by the more conventional routes.Author: Deep Kwatra, Ashim K Mitra
https://www.sciencedirect.com/science/article/pii/S093964111500260X
Dual drug delivery from vitamin E loaded contact lenses for glaucoma therapy ... As demonstrated by Peng et al. , the presence of vitamin E diffusion barriers in the contact lens reduces the drug transport rate by increasing ... M.T. Burke, B.E. Carbia, C. Plummer, A. ChauhanExtended drug delivery by contact lenses for glaucoma therapy. J ...Author: Kuan-Hui Hsu, Blanca E. Carbia, Caryn Plummer, Anuj Chauhan
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