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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944611/
Thus, bacterial ghost technology would definitely replace use of live or attenuated bacteria as vaccines. A number of reports support the effectiveness of bacterial ghost for the delivery of drugs, vaccines, and biotherapeutics in mammals.[38,39] The future of bacterial ghost would lie on their ability to deliver drug to target sites. However ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037582/
The Bacterial Ghost (BG) platform technology is an innovative system for vaccine, drug or active substance delivery and for technical applications in white biotechnology. BGs are cell envelopes derived from Gram-negative bacteria. BGs are devoid of all ...
https://www.researchgate.net/publication/304368351_Use_of_Bacterial_Ghosts_as_Novel_Drug_Delivery_Systems_to_Improve_Cancer_Treatment
The Bacterial Ghost (BG) platform technology is an innovative system for vaccine, drug or active substance delivery and for technical applications in white biotechnology. BGs are cell envelopes ...
https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-017-0442-5
Jun 24, 2017 · Bacterial ghosts (BG) are empty cell envelopes derived from Gram-negative bacteria. They contain many innate immunostimulatory agonists, and are potent activators of a broad range of cell types involved in innate and adaptive immunity. Several considerable studies have demonstrated the effectiveness of BG as adjuvants as well as their ability to induce proinflammatory cytokine production …Author: Irshad A. Hajam, Pervaiz A. Dar, Gayeon Won, John Hwa Lee
https://www.sciencedirect.com/science/article/pii/S0264410X1000928X
Aug 16, 2010 · The bacterial ghost (BG) system developed during the past few years represents a new platform in vaccine development .BGs, empty bacterial shells of Gram-negative bacteria, have been developed as a novel potent carrier and adjuvant system for the delivery of DNA vaccines , , , , .BGs are produced by protein E-mediated lysis of Gram-negative bacteria.Author: Pavol Kudela, Verena Juliana Koller, Werner Lubitz
https://pdfs.semanticscholar.org/f174/0471f3343aaac2b8f41b857e9d75bd60a001.pdf
cells. The bacterial ghost system is a novel vaccine delivery system usually in that it combines excellent natural intrinsic adjuvant properties with versatile carrier functions for foreign antigens. The efficient tropism of bacterial ghosts for antigen presenting cells promotes the generation of both cellular and humoral responses
https://www.sciencedirect.com/science/article/pii/S0168365903004437
The in vitro release profile of DOX–ghosts demonstrated that the loaded drug was non-covalently associated with the bacterial ghosts and that the drug delivery vehicles themselves represent a slow release system. ... Ghost-mediated delivery of DOX to Caco-2 cells.Author: Susanne Paukner, Gudrun Kohl, Werner Lubitz
https://www.tandfonline.com/doi/abs/10.3109/10611860310001593366
The purpose of the present study was to develop a drug delivery model for water soluble drug substances using the bacterial ghost platform technology. Bacterial ghosts are non-denatured bacterial cell envelopes that are produced by the plasmid encoded gene E mediated lysis. We present a novel method to fill and seal bacterial ghosts for the ...Author: Susanne Paukner, Gudrun Kohl, Katri Jalava, Werner Lubitz
https://www.tandfonline.com/doi/abs/10.1517/17425247.3.1.11
Bacterial ghosts combine excellent natural or engineered adhesion properties with versatile carrier functions for drugs, proteins and DNA plasmids or DNA minicircles. The simplicity of both bacterial ghost production and packaging of drugs and/or DNA makes them particularly suitable for …Author: Susanne Paukner, Thomas Stiedl, Pavol Kudela, Jozef Bizik, Firas Al Laham, Werner Lubitz
https://www.researchgate.net/publication/51059415_Bacterial_Ghosts_as_antigen_and_drug_delivery_system_for_ocular_surface_diseases_Effective_internalization_of_Bacterial_Ghosts_by_human_conjunctival_epithelial_cells
The Bacterial Ghost (BG) platform technology is an innovative system for vaccine, drug or active substance delivery and for technical applications in white biotechnology. BGs are cell envelopes ...
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