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https://www.sciencedirect.com/science/article/pii/S0024320520302988
Another important strategy in virus mediated vaccine delivery is the viral vector-DC vaccine, virus vector-Car T. Targeting transgene expression to dendritic cells (DCs) has become a promising approach for guiding the immune system towards immunity or tolerance.Author: Balamurugan Shanmugaraj, Lohanathan Bharathi Priya, B. Mahalakshmi, Shanmugam Subbiah, Rouh-Mei Hu, ...
https://www.sciencedirect.com/science/article/pii/S0165247817306028
LAB are non-pathogenic, they can overcome some of the limitations of live-attenuated bacteria vaccine vector and are attractive alternative to attenuated bacteria. Moreover, LAB are good candidates for the development of oral vaccines and satisfy the requirements of delivery …Author: Chengchao Ding, Junfei Ma, Qingli Dong, Qing Liu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693226/
Nov 10, 2015 · Among all the vaccine delivery systems that have been developed, including viral particles, attenuated viral vectors, liposomes, ISCOMs and plant-based oral vaccines, live-attenuated bacterial vectors are the most characterized vehicles for mucosal vaccine delivery. ... Bacteria are used as a vector to deliver the genetic information into the ...Author: Ivan Y. C. Lin, Thi Thu Hao Van, Peter M. Smooker
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323283/
Keywords: bacterial vector, vaccine delivery system, DNA vaccine, cancer vaccine, antigen presentation Introduction The strategy of using live bacterial cells as vehicles to deliver recombinant antigens has emerged over the past two decades as an interesting alternative for the development of …Author: Adilson José da Silva, Teresa Cristina Zangirolami, Maria Teresa Marques Novo-Mansur, Roberto de Cam...
https://www.mdpi.com/2076-3271/6/2/27/pdf
increase DNA vaccine efficiency. Chemical delivery systems, such as using micro particles [11,15] and nanoparticles [16,17], have successfully increased DNA vaccine delivery. Another potential delivery system to improve DNA vaccine delivery is the use of a live bacterial vector as the carrier.Author: Valentina Yurina
https://medicalxpress.com/news/2015-04-nanoparticle-coated-bacteria-cancer-vaccine.html
Apr 16, 2015 · Nanoparticle-coated bacteria can act as a vaccine vector, delivering vaccines that evoke an antitumor immune response. As shown here, the nanoparticles are …
https://www.mdpi.com/2076-393X/3/4/940
Genetically attenuated microorganisms, including pathogenic and commensal bacteria, can be engineered to carry and deliver heterologous antigens to elicit host immunity against both the vector as well as the pathogen from which the donor gene is derived. These live attenuated bacterial vectors have been given much attention due to their capacity to induce a broad range of immune responses ...Author: Ivan Y. C. Lin, Thi Thu Hao Van, Peter M. Smooker
https://www.creative-biolabs.com/vaccine/bacterial-vector-vaccine-design.htm
An ideal vaccine vector should not only be able to trigger potent innate but adaptive immune response in the inoculated host. The use of live bacteria as a vector to deliver heterologous antigens is an effective and original alternative to the development of new vaccines.
https://www.researchgate.net/publication/323973670_Live_Bacterial_Vectors-A_Promising_DNA_Vaccine_Delivery_System
Proposed DNA vaccine delivery system using a live bacterial vector. (1) Bacteria are recognized by immune cells and phagocytized; (2) Inside the cells, bacteria fuse with the lysosome and form ...
https://www.hindawi.com/journals/jir/2019/8303648/
Intradermal immunization for vaccine delivery is an upcoming strategy showing significant advantages over conventional vaccination routes. In particular, in the last few years, intradermal vaccination has gained momentum as an alternative and more effective vaccine delivery route, both from a scientific and a commercial point of view (Table 3).Author: E. Criscuolo, V. Caputo, V. Caputo, R. A. Diotti, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum, N. ...
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