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https://www.sciencedirect.com/science/article/pii/S2211383513000919
The availability of novel lipid excipients with acceptable regulatory and safety profiles coupled with their ability to enhance oral bioavailability has helped in the development of lipid based formulations as a means for drug delivery. Lipid-based drug delivery (LBDD) systems have gained much importance in the recent years due to their ability ...Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.hindawi.com/journals/jphar/2014/801820/
The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374933/
Emulsions. Another approach to increase the bioavailability of poorly water solule drugs is to formulate them in lipid emulsions. Bioavailability studies in humans were carried out using o/w-emulsions, aqueous suspensions and commercial tablets (Bates and Sequeira 1975) of griseofulvin which is an antifungal antibiotic and it is commonly used in the treatment of dermatophyte infections in humans.
https://www.sciencedirect.com/science/article/pii/S0168365906003622
Oct 10, 2006 · This study investigates the submicron lipid emulsion as a potential parenteral drug delivery system for nalbuphine and its ester prodrugs. Submicron emulsions were prepared using egg phospholipid as the main emulsifier, various co-emulsifiers were also incorporated, including Brij 30, Brij 98, and stearylamine.Author: Jhi Joung Wang, K. C. Sung, Oliver Yoa Pu Hu, Chih Hui Yeh, Jia You Fang
https://drug-dev.com/lipid-based-delivery-are-lipid-based-drug-delivery-systems-in-your-formulation-toolbox/
ABSTRACT. This article reviews the causes of poor bioavailability for drugs. It provides an introduction to lipid-based drug delivery systems, and how the formulation approach can be used to overcome impediments to good bioavailability of therapeutic actives, including poor water solubility, low permeability, and degradation by stomach acid or enzymes in vivo.
https://www.rxlist.com/intralipid-20-drug.htm
Sep 04, 2019 · intralipid® 20% (20% i.v. fat emulsion) in excel® container. description. intralipid® 20% (20% i.v. fat emulsion) (a 20% intravenous fat emulsion) is a sterile, non-pyrogenic fat emulsion prepared for intravenous administration as a source of calories and essential fatty acids.it is made up of 20% soybean oil, 1.2% egg yolk phospholipids, 2.25% glycerin, and water for injection.
https://www.researchgate.net/publication/261110084_A_GLIMPSE_ON_SOLID_LIPID_NANOPARTICLES_AS_DRUG_DELIVERY_SYSTEMS
Solid lipid nanoparticles are at the vanguard of the rapidly budding field of nanotechnology with numerous prospective applications in drug delivery, clinical research, in addition to other ...
https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.1987.tb45793.x
Lipid Emulsions as Drug Delivery Systems. STANLEY S. DAVIS. Pharmacy Department University of Nottingham Nottingham, United Kingdom. Search for more papers by this author. CLIVE WASHINGTON. Pharmacy Department University of Nottingham Nottingham, United Kingdom.Author: Stanley S. Davis, Clive Washington, Philip West, Lisbeth Illum, Garry Liversidge, Larry Sternson, Ri...
https://www.researchgate.net/publication/6831681_Submicron_lipid_emulsion_as_a_drug_delivery_system_for_nalbuphine_and_its_prodrugs
This study investigates the submicron lipid emulsion as a potential parenteral drug delivery system for nalbuphine and its ester prodrugs. Submicron emulsions were prepared using egg phospholipid ...
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.2042-7158.2010.01107.x
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs jphp_1107 1622..1636 Anette Müllertza,b, Anayo Ogbonnaa, Shan Rena and Thomas Radesc aDepartment of Pharmaceutics and Analytical Chemistry, bBioneer:FARMA, The Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark and cSchool of Pharmacy, University …Author: Anette Müllertz, Anayo Ogbonna, Shan Ren, Thomas Rades
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