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https://gsconlinepress.com/journals/gscbps/sites/default/files/GSCBPS-2019-0030.pdf
1.1. Advantages of ocular drug delivery system [12] The merits of ODDS are followings: Increased accurate dosing, to overcome the side effects of pulsed dosing produced by conventional systems. To provide sustained and controlled drug delivery. To increase the ocular bioavailability of drug by increasing the corneal contact time.Author: Kumari Beena
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781321/
Sep 06, 2019 · For quite a few decades, the mechanism of specific drug delivery to ocular milieu was indeed a challenge [201,202]. The common pharmaceutical formulations applied to this purpose, drugs applied as eye drops, suffered downsides which, by turn, required the implementation of distinct carriers aimed in ocular administration route.Author: Eliana B. Souto, João Dias-Ferreira, Ana López-Machado, Miren Ettcheto, Amanda Cano, Antonio Camins ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Table V summarizes recent advances in the use of fibrin sealant for ocular drug delivery. This approach was successfully studied for delivery of tobramycin (keratitis), topotecan, carboplatin (retinoblastoma), and insulin (diabetic retinopathy).Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.researchgate.net/publication/332012889_Ocular_drug_delivery_system_Approaches_to_improve_ocular_bioavailability
Ocular drug delivery system: Approaches to improve ocular bioavailability Kumari Beena * School of Medical and Allied Sciences GD Goenka University, Gurugram, India.
https://www.healio.com/ophthalmology/cornea-external-disease/news/print/ocular-surgery-news/%7Bd69fee03-15c5-4fbd-a090-4f8a5b294c17%7D/understanding-topical-ophthalmic-drug-delivery-how-much-gets-in
To improve ocular topical drug delivery, drug designers have developed strategies that minimize precorneal drug loss and maximize corneal drug absorption. They use three main approaches to deal ...
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Acquire sound knowledge of various approaches to increase ocular drug absorption. Understand the utility, recent progress, and specific development issues relating to dendrimers, cyclodextrins, nanoparticles, liposomes, nanomicelles, microneedles, implants, in situ gelling systems, and contact lens in ocular drug delivery.
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