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https://www.sciencedirect.com/science/article/pii/B9781845690700500047
Biodegradable polymers have truly revolutionized controlled drug delivery design and biomaterial applications for implants and tissue engineering. With the help of biodegradable stents, clinicians can site-specifically control drug release to treat coronary artery disease through delivery of traditional small molecules and now gene therapy.Author: G. S. Kwon, D. Y. Furgeson
https://www.pharmatutor.org/articles/biodegradable-polymers-role-drug-delivery
The use of biodegradable polymer in drug delivery grew from the search for polymers that could be employed as degradable sutures. Synthetic polymers such as poly (glycolic acid) were first developed in the 1950is and their poor hydrolytic stability made them unsuitable for permanent applications.
https://biomedres.us/fulltexts/BJSTR.MS.ID.002056.php
Many biodegradable polymers have been successfully fabricated into a number of devices for drug delivery including microspheres, microcapsules and nanoparticles [21,22]. There are several ways that polymers can be utilised in drug delivery, including diffusion controlled systems, swelling controlled devices and particulate systems such as polymer-drug conjugates.Author: Kiran Dhaliwal, Priya Dosanjh, Jose Sanchez Payá
https://link.springer.com/chapter/10.1007%2F978-1-4614-0881-9_5
Sep 27, 2011 · This chapter is focused on the use of biodegradable polymers in long acting injectable drug delivery systems with an emphasis on marketed products. An overview is provided of how the chemical structures and physical properties of these polymers impact functionality of drug delivery systems and how to strategically select polymers for different ...Author: Jamie Tsung, Diane J. Burgess
https://www.sciencedirect.com/science/article/pii/S0014305719305920
Applications of biodegradable polymeric nanoparticles 5.1. Biodegradable polymers in targeted drug delivery. 5.2. Vaccination with nanoparticles. Administration of vaccine using nanoparticles is known as... 5.3. Nanoparticles in inflammatory diseases. 5.4. Nanoparticles in ocular delivery. To ...Author: Shiv Kumar Prajapati, Ankit Jain, Aakanchha Jain, Sourabh Jain
http://www.jsrponline.com/Archives_html.php?htmlcode=565
For some degradable polymers, most notably the Polyanhydrides and Polyorthoesters, the degradation occurs only at the surface of the polymer, resulting in a release rate that is proportional to the surface area of the drug delivery system. Biodegradable polymers mainly investigated for drug delivery applications are of either natural or synthetic origin.
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