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https://www.sciencedirect.com/science/article/pii/0169409X89900276
The field of liposome targeting has developed rapidly in the past 10 years as a multidisciplinary approach to the controlled delivery of bioactive molecules. Liposomes as delivery vehicles offer several benefits over the administration of free compounds as therapeutic devices.Author: Stephen Wright, Leaf Huang
https://www.sciencedirect.com/science/article/abs/pii/0169409X89900276
Antibody-directed liposomes as drug-delivery vehicles. Author links open overlay panel Stephen Wright Leaf Huang. Show moreAuthor: Stephen Wright, Leaf Huang
https://www.ncbi.nlm.nih.gov/pubmed/3756852
The antibody-directed Protein A liposomes were also 10-fold more potent than liposomes conjugated directly to specific antibody against the AKR/J SL2. We examined the effect of antibody specificity, concentration, and isotype on liposome-mediated drug delivery to AKR/J SL2 cells.Author: Katherine K. Matthay, Timothy D. Heath, Christopher C. Badger, Irwin D. Bernstein, Demetrios Papahad...
http://news.illinois.edu/news/09/0806drugdelivery.html
University of Illinois researchers report that they have assembled a new cancer drug delivery system that, in cell culture, achieves all of the above. The findings appear this month in the journal Angewandte Chemie. The team began with the knowledge that small, membrane-bound compartments, called liposomes, are useful as drug-delivery vehicles.
https://www.researchgate.net/publication/232057603_Liposomal_Delivery_of_Peptides_and_Proteins
Liposomal Delivery of Peptides and Proteins. ... Antibody-directed liposomes as drug-delivery vehicles. ... Liposomes as delivery vehicles offer several benefits over the administration of free ...
https://www.nature.com/articles/bjc199211
Jan 01, 1992 · Cite this article. Morgan, J., MacRobert, A., Gray, A. et al. Use of photosensitive, antibody directed liposomes to destroy target populations of cells in bone marrow: a potential purging method ...Author: J Morgan, AJ MacRobert, AG Gray, ER Huehns
http://watcut.uwaterloo.ca/webnotes/Pharmacology/DrugDelivery.html
Liposomes as drug delivery vehicles : Liposomes are vesicles consisting of natural or synthetic phospholipids. They can vary widely in size, but the ones used for drug delivery are most often between 50 and 200 nm in diameter. ... the monoclonal antibody directed against the tumor-related growth factor receptor Her2/neu. ...
https://pubs.acs.org/doi/abs/10.1021/bi00266a005
Antibody-directed liposomes as drug-delivery vehicles. Advanced Drug Delivery Reviews 1989, 3 (3) , 343-389. DOI: 10.1016/0169-409X(89)90027-6. Madeleine Lüscher-Mattli. Effect of the mitogenic lectin concanavalin A on the thermotropic behavior of glycosyl-free cationic lipids and their mixtures with zwitterionic lipids. ...Author: Theodore F. Taraschi, Arnold T. M. Van der Steen, Ben De Kruijff, Charles Tellier, Arie J. Verkleij
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC19511/
Nov 26, 1996 · Immunoliposomes (antibody-directed liposomes) were used in the present study for delivery of the antineoplastic agent daunomycin to the rat brain. A coupling procedure was introduced, which allows conjugation of a thiolated antibody to maleimide-grafted 85-nm liposomes sterically stabilized with PEG.Author: Joerg Huwyler, Dafang Wu, William M. Pardridge
https://link.springer.com/article/10.1007/BF03259058
Oct 30, 2012 · Antibody-directed liposomes, or immunoliposomes, have been extensively examined for potential applications for site-specific drug delivery. A wide variety of cytotoxic drugs, including conventional low molecular weight cytotoxic drugs, proteins, peptides, oligonucleotides and plasmid DNA, have been formulated in immunoliposomes.Author: Atsuhide Mori, Leaf Huang
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