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https://www.ncbi.nlm.nih.gov/pubmed/28657549
Aug 18, 2017 · In this study, the anti-hTERT blocking monoclonal antibody (mAb), as the model intrabody, was used to prepare nanoparticles (NPs), followed by the encapsulation of erythrocyte membrane (EM), to obtain the EM-coated anti-hTERT mAb NPs delivery system. The final NPs showed a z-average hydrodynamic diameter of about 197.3 nm.Author: Lipeng Gao, Lin Han, Xiaoling Ding, Jiaojiao Xu, Jing Wang, Jianzhong Zhu, Weiyue Lu, Jihong Sun, Le...
https://www.sciencedirect.com/science/article/pii/S1525001616316744
Monoclonal antibody (mAb) delivery by gene transfer in vivo may be an attractive alternative to current mAb therapies for applications that require long-term therapy. This article describes a transfer system that allows inducible high-level expression of unmodified mAbs in vivo.A recombinant adeno-associated viral (rAAV) vector is used that comprises an expression cassette consisting of a ...Author: Jianmin Fang, Saili Yi, Andrew Simmons, Guang Huan Tu, Minh Nguyen, Thomas C Harding, Melinda VanRoe...
https://www.ncbi.nlm.nih.gov/pubmed/29973504
Jul 04, 2018 · Overview of Antibody Drug Delivery. ... with the identification of new drug targets being one key barrier for new antibody development. There are many opportunities for developing antibody formulations for better patient compliance, cost savings and …Author: Sahar Awwad, Ukrit Angkawinitwong
https://www.nih.gov/news-events/news-releases/drug-delivery-technology-leads-sustained-hiv-antibody-production-nih-study
Mar 09, 2020 · The drug-delivery system developed by scientists at NIAID’s Vaccine Research Center (VRC) uses adeno-associated virus serotype 8 (AAV8) to deliver an antibody gene. AAVs — small viruses that do not cause disease in humans — have proven to …
https://www.organicfacts.net/drug-delivery-antibody-production.html
Mar 11, 2020 · Production of antibodies could mean protection against diseases that are difficult to treat. Hence, the discovery of a novel method of drug delivery that could boost antibody production in the body means humanity being a step closer to winning the fight against the disease. A recent study has ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)31674-4
Jun 01, 2007 · Monoclonal antibody (mAb) delivery by gene transfer in vivo may be an attractive alternative to current mAb therapies for applications that require long-term therapy. This article describes a transfer system that allows inducible high-level expression of unmodified mAbs in vivo. A recombinant adeno-associated viral (rAAV) vector is used that comprises an expression cassette consisting of a ...Author: Jianmin Fang, Saili Yi, Andrew Simmons, Guang Huan Tu, Minh Nguyen, Thomas C Harding, Melinda VanRoe...
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