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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025929/
5 Make sure that you filter the antagomiR through a 0.22 μM filter to ensure the sterility. Also use sterile technique while filling, handling, and implanting Alzet Osmotic pumps. 6 Place the pumps with saline for at least 4–60 h before implantation (depends upon the pump used) in order to prime the pumps for continuous delivery of the drugs.Author: Chinavenmeni S. Velu, H. Leighton Grimes
https://erj.ersjournals.com/content/48/suppl_60/PA4028
Sep 01, 2016 · After both intraperitoneal and intravenous administration to pregnant mice [at embryonic stage (E)17], no impact of antagomiR-29a-3p on miR-29a-3p expression levels was observed in the lung, liver, heart, kidney, and brain of the pregnant mothers on the day of pup delivery [post-natal (P)1)].Author: Jonas Hönig, Ivana Mizíková, Claudio Nardiello, Werner Seeger, Rory Morty
https://www.ncbi.nlm.nih.gov/pubmed/30141567
In contrast to the siRNA/miRNA delivery methods, the antagomiR delivery is based on strand displacement, in which the antagomiR-152 is displaced by oncomiR-152 followed by a surface-enhanced Raman spectroscopy signal drop. This enables both cancer cell diagnosis and in vitro real-time monitoring of the antagomiR release.Author: Mohsen Mohammadniaei, Taek Lee, Bapurao G. Bharate, Jinho Yoon, Hye Kyu Choi, Soo‐jeong Park, Jungho...
https://www.sciencedirect.com/science/article/pii/S0168365915302431
First, antagomir delivery was observed in areas with a high density of cells, indicating intracellular and extracellular antagomir delivery (Fig. 4H + I, arrow-heads). Second, antagomir delivery was observed into cardiomyocytes displaying a normal morphology and no influx of cells (Fig. 4J + K, arrows).Author: Rick F.J. Kwekkeboom, Joost P.G. Sluijter, Ben J. van Middelaar, Corina H. Metz, Maike A. Brans, Ott...
https://www.sciencedirect.com/science/article/pii/S0142961215001179
The data from laser light scattering measurement showed that the average hydrodynamic diameter of (D-Asp 8)-liposome-antagomir-148a was 150 nm (Fig. 1a) and the zeta potential of (D-Asp 8)-liposome-antagomir-148a was about −10 mV.Meanwhile, the data from Quant-iT™ RiboGreen ® RNA assay demonstrated that the encapsulation efficiency of the (D-Asp8)-liposome was about 80.15% for …Author: Jin Liu, Lei Dang, Defang Li, Chao Liang, Xiaojuan He, Xiaojuan He, Heng Wu, Heng Wu, Airong Qian, A...
https://www.bio.purdue.edu/lab/kasinski/manuscripts/Mol%20Ther%20Nucleic%20Acids%202012%20Kasinski.pdf
Targeted therapeutic delivery of antagomir-221 2 Following systemic delivery of the cholesterol-tagged anti-miR-221 to orthotopic tumors, the G1 cell-cycle checkpoint inhibitors p27Kip1 and p57Kip2 were elevated approximately threefold. Increased p27Kip1 and p57Kip2 most likely contrib-uted to loss of the cellular proliferation marker, Ki-67, and
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(16)30070-1
Arresting the Culprit: Targeted Antagomir Delivery to Sequester Oncogenic miR-221 in HCC. ... Following systemic delivery of the cholesterol-tagged anti-miR-221 to orthotopic tumors, the G1 cell-cycle checkpoint inhibitors p27 Kip1 and p57 Kip2 were elevated approximately threefold.Author: Andrea L Kasinski, Frank J Slack
https://www.researchgate.net/publication/327203542_Bifunctional_AuBi_2_Se_3_Core-Shell_Nanoparticle_for_Synergetic_Therapy_by_SERS-Traceable_AntagomiR_Delivery_and_Photothermal_Treatment
In contrast to the siRNA/miRNA delivery methods, the antagomiR delivery is based on strand displacement, in which the antagomiR‐152 is displaced by oncomiR‐152 followed by a …
https://www.researchgate.net/publication/273953164_A_naturally_derived_dextran-peptide_vector_for_microRNA_antagomir_delivery
A naturally derived dextran–peptide vector for microRNA antagomir delivery. ... Dex10-R5H5(40%) loaded with antagomir-149 could reduce the level of endogenous microRNA-149 by 76% and it is more ...
https://www.onlinelibrary.wiley.com/doi/full/10.1002/smll.201802934
Aug 23, 2018 · In contrast to the siRNA/miRNA delivery methods, the antagomiR delivery is based on strand displacement, in which the antagomiR‐152 is displaced by oncomiR‐152 followed by a surface‐enhanced Raman spectroscopy signal drop. This enables both cancer cell diagnosis and in vitro real‐time monitoring of the antagomiR release.Author: Mohsen Mohammadniaei, Taek Lee, Bapurao G. Bharate, Jinho Yoon, Hye Kyu Choi, Soo‐jeong Park, Jungho...
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