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https://www.sciencedirect.com/science/article/pii/0168365996013338
In summary, an in situ gelling system formed by an interpolymer complex between PEG and PMA shows its potential utility as a parenteral controlled- release drug delivery system. Such a system could be useful for sustained systemic and local administra- tion of low molecular weight chemotherapeutic agents and macromolecules.Author: Bert O. Haglund, Rajashree Joshi, Kenneth J. Himmelstein
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165193/
Jun 01, 2014 · In situ gelling systems are polymeric formulations that are in sol forms before entering in the body, but change to gel forms under the physiological conditions. The sol-gel transition depends on one or a combination of different stimuli, like pH change, temperature modulation, solvent exchange, ultra violet irradiation and the presence of specific ions or molecules.Author: Maryam Kouchak
https://www.sciencedirect.com/science/article/pii/S0939641104000463
Biodegradable injectable in situ forming drug delivery systems represent an attractive alternative to microspheres and implants as parenteral depot systems. Their importance will grow as numerous proteins will lose their patent protection in the near future.Author: C.B Packhaeuser, J Schnieders, C.G Oster, T Kissel
https://www.researchgate.net/publication/8414063_In_situ_forming_parenteral_drug_delivery_systems_An_overview
Despite the potential of in situ gelling systems to facilitate controlled drug release (Packhaeuser et al., 2004), they have not been explored as delivery systems for mitomycin-C in enhancing the ...
https://www.researchgate.net/publication/326246294_INSITU_2018
The 'in situ gel' system has emerged as one of the best novel drug delivery systems; it helps for the sustained and controlled release of the drugs by its special characteristic feature of 'Sol to ...
https://www.researchgate.net/publication/228097758_Injectable_In-Situ_Gelling_Controlled_Release_Drug_Delivery_System
One of the such system is injectable in-situ gelling system This biodegradable injectable in-situ gelling drug delivery system offer attractive opportunities for protein, anti cancer or NSAIDs ...
https://www.researchgate.net/publication/264240825_In-situ_Forming_Parenteral_Drug_Delivery_A_New-fangled_Loom_In_Therapeutics
Hence, in-situ forming parenteral drug delivery systems seems promising, as they offers a range of advantages over conventional parenteral delivery systems, and may escort to a new path in ...
https://www.researchgate.net/publication/266027688_In_Situ_Gelling_Systems_for_Drug_Delivery
In Situ Gelling Systems for Drug Delivery.pdf. ... parenteral drug delivery ... The purpose of the present study is to develop a pH-triggered in situ gel system for ophthalmic delivery of DRZ for ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865781/
In situ forming polymeric formulations are drug delivery systems that are in sol form before administration in the body, but once administered, undergo gelation in situ, to form a gel. The formation of gels depends on factors like temperature modulation, pH change, presence of ions and ultra violet irradiation, from which the drug gets released in a sustained and controlled manner.
https://www.slideshare.net/shreeraj9183/insitu-gel-drug-delivery-system
Aug 28, 2012 · Applicability of In Situ Drug DeliverySystemIn situ forming polymeric systems for Oral administration Pectin, xyloglucan and gellan gum are the natural polymers used for in situ oral drug delivery systems The main advantage of using pectin for these formulations is that it is water soluble, so organic solvents are not necessary in the formulation In situ gelling gellan formulation as vehicle for oral delivery …
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