Amphiphilic Linear-Dendritic Block Copolymers For Drug Delivery

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Linear–dendritic block copolymer for drug and gene delivery

    https://www.sciencedirect.com/science/article/pii/S0928493116300431
    AB diblock linear–dendritic copolymers contain the linear A block and dendritic B block, while ABA triblock linear–dendritic copolymers use B as the linear block and A as the dendritic block.Author: Xiaohui Fan, Yanli Zhao, Wei Xu, Lingbing Li

Amphiphilic linear-dendritic block copolymers for drug ...

    http://dspace.mit.edu/handle/1721.1/42432
    The linear-dendritic block copolymer synthesized was found to be a promising candidate for drug delivery due to its relative stability in aqueous solution and its drug encapsulation …

Amphiphilic block copolymers for drug delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/S0022354916312849
    Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical applications ranging from sustained-release technologies to gene delivery. The utility of ABCs for delivery of therapeutic agents results from their unique chemical composition, which is characterized by a hydrophilic block that is chemically tethered to a hydrophobic block.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon

Amphiphilic block copolymers for drug delivery - Adams ...

    https://www.onlinelibrary.wiley.com/doi/10.1002/jps.10397
    Because each ABC has unique advantages with respect to drug delivery, it may be possible to choose appropriate block copolymers for specific purposes, such as prolonging circulation time, introduction of targeting moieties, and modification of the drug‐release profile.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon

Amphiphilic linear-dendritic block copolymers for drug ...

    https://core.ac.uk/display/4406987
    In this thesis, an amphiphilic linear-dendritic block copolymer was designed, synthesized, and applied as a new polymeric drug delivery platform. First, to develop the drug delivery vehicle, an ABA dendritic-linear-dendritic block copolymer consisting of poly(amidoamine) (PAMAM) and poly(propylene oxide) (PPO) was synthesized.

Linear-dendritic block copolymer for drug and gene delivery

    https://www.researchgate.net/publication/291423144_Linear-dendritic_block_copolymer_for_drug_and_gene_delivery
    A novel amphiphilic linear-dendritic block copolymer, semi-polyamidoamine-b-poly (D, L-lactic acid) (PALA) was synthesized and evaluated for its potential as a drug delivery system in this study.

Amphiphilic block copolymers in drug delivery: advances in ...

    https://www.researchgate.net/publication/327918925_Amphiphilic_block_copolymers_in_drug_delivery_advances_in_formulation_structure_and_performance
    Download Citation Amphiphilic block copolymers in drug delivery: advances in formulation structure and performance Introduction: Nanostructured delivery vehicles can address key challenges ...

Amphiphilic Hybrid Dendritic-Linear Molecules as ...

    https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.8b00190
    Nanoparticles based on hybrid block copolymers had been expected as effective nanocarriers for hydrophobic drug delivery. Herein, the novel dendritic-linear molecules from OEG dendron conjugated with octadecylamine (G2-C18) was designed, synthesized, and further applied as nanocarrier to prepare 10-hydroxycamptothecin (HCPT) nanoparticles via antisolvent precipitation method. It seemed that ...Author: Yifei Guo, Ting Wang, Ting Wang, Shuang Zhao, Meihua Han, Zhengqi Dong, Xiangtao Wang, Yanhong Wang

Self-Assembling Hybrid Linear-Dendritic Block Copolymers ...

    https://www.mdpi.com/2079-4991/9/2/161/pdf
    Abstract: Two series of amphiphilic block copolymers with a hybrid linear-dendritic structure are presented. The compounds consisted of a hydrophilic poly (ethylene glycol) (PEG) block and a 2,20-bis(hydroxymethyl)propionic acid (bis-MPA) dendron functionalized with stearic acid chains that impart a hydrophobic nature to the block.Author: Elisabetta Fedeli, Alexandre Lancelot, Juan Manuel Dominguez, José Luis Serrano, Pilar Calvo, Teresa...

Architecture based selectivity of Amphiphilic block ...

    https://www.sciencedirect.com/science/article/pii/S1381514819312386
    Current study is targeted to compare the architecture based selectivity of amphiphilic block copolymers for drug delivery applications. It is shown that SPM are found to be superior than LPM in context of CMC, drug loading efficiency, and drug release behavior.Author: Imdad Ali, Faheem Kareem, Sana Rahim, Samina Perveen, Shakil Ahmed, Muhammad Raza Shah, Muhammad Imr...

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