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https://www.researchgate.net/publication/6938146_AlginatePEIDNA_polyplexes_A_new_gene_delivery_system
The alginate-coated PD polyplexes as a new gene delivery system can improve transfection efficiency in high serum concentration with low cytotoxicity to C3 cells. Discover the world's research 16 ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831726/
Guinea pigs immunized with the diphtheria toxoid-loaded alginate nanoparticles showed highest humoral immune response than conventional vaccine. It is concluded that, with regard to the desirable properties of nanoparticles and high immunogenicity, alginate nanoparticles could be considered as a new promising vaccine delivery and adjuvant system.
https://link.springer.com/article/10.1007%2FBF02931086
Abstract. A novel non-viral gene delivery system comprised of a DNA/PEI/Alginate (DPA) polyplex was prepared and assessedin vitro andin vivo.Coating the positively charged DNA/PEI (DP) complex with a polyanion resulted in a high level ofin vitro reporter gene transfection in the presence of 50 vol% serum due to the minimized cytotoxicity of PEI and the reduced nonspecific interactions with ...Author: Ge Jiang, Sang-Hyun Min, Eun Ju Oh, Sei Kwang Hahn
https://www.sciencedirect.com/science/article/pii/S1671292711600679
This study was carried out to investigate the transfection effect of exogenous gene into plant protoplast cell mediated by polyethylenimine (PEI) nanovector, based on PEI gene delivery system in the field of medical science. PEI/DNA complexes were prepared by using PEI polymer to bind the plant expression plasmid, pCMl205-GFPn.Author: Ying Li, Hai-xin Cui, Yu Song, Yao Li, Jin-li Huang
http://www.ijpsonline.com/articles/alginate-nanoparticles-as-a-promising-adjuvant-and-vaccine-delivery-system.html
The aim of the present study was to develop a new vaccine formulation based on alginate NPs containing diphtheria toxoid (DT) as a novel and promising adjuvant and vaccine delivery system. Materials and Methods. DT (5600 Lf/ml), diphtheria toxin, and antitoxin of DT were obtained from Razi Vaccine and Serum Research Institute, Karaj, Iran.Author: F Sarei, N Mohammadpour Dounighi, H Zolfagharian, P Khaki, S Moradi Bidhendi
https://www.sciencedirect.com/science/article/pii/S0142961209001161
We discovered a vector coated by γ-polyglutamic acid (γ-PGA) for effective and safe gene delivery. In order to develop a useful non-viral vector, we prepared several ternary complexes constructed with pDNA, polyethylenimine (PEI), and various polyanions, such as polyadenylic acid, polyinosinic–polycytidylic acid, α-polyaspartic acid, α-polyglutamic acid, and γ-PGA.Author: Tomoaki Kurosaki, Takashi Kitahara, Shintaro Fumoto, Koyo Nishida, Junzo Nakamura, Takuro Niidome, Y...
https://www.researchgate.net/publication/259155855_Alginate_Nanoparticles_as_a_Promising_Adjuvant_and_Vaccine_Delivery_System
Alginate Nanoparticles as a Promising Adjuvant and Vaccine Delivery System.pdf ... Alginate Nanoparticles as a Promising Adjuvant and Vaccine Delivery System.pdf ... PEI/DNA polyplexes: A …
https://www.jstage.jst.go.jp/article/bpb/36/11/36_b13-00479/_html
Alginate/PEI/DNA polyplexes: a new gene delivery system. Yao Xue Xue Bao , 41 , 439–445 (2006). 30) Khalil I, Kogure K, Akita H, Harashima H. Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery.Author: Kosuke Kanda, Yukinobu Kodama, Tomoaki Kurosaki, Masanobu Imamura, Hiroo Nakagawa, Takahiro Muro, No...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764302/
For a non-viral gene delivery system to be clinically effective, it should be non-toxic, compatible with biological components, and highly efficient in gene transfection. With this goal in mind, we investigated the gene delivery efficiency of a ternary ...Author: Peisheng Xu, Griffin K. Quick, Yoon Yeo
https://www.deepdyve.com/lp/elsevier/ternary-complexes-of-pdna-polyethylenimine-and-polyglutamic-acid-for-KgdpILWwtt
May 01, 2009 · Read "Ternary complexes of pDNA, polyethylenimine, and γ-polyglutamic acid for gene delivery systems, Biomaterials" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
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